Do Bonding Disruptions Occur More Often in Children With Asthma Than in Non-asthmatic Populations?

NCT ID: NCT02158338

Last Updated: 2015-06-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-06-30

Study Completion Date

2015-03-31

Brief Summary

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Six studies have preceded this project. Three studies suggested that there is a significant connection between pediatric asthma and disruptions in maternal-infant bonding (Feinberg, 1988; Schwartz, 1988; Pennington, 1991). Three studies suggested that children with asthma benefit from a type of therapy that improves bonding with their mothers (Madrid, Ames, Skolek, \& Brown, 2000; Madrid, Ames, Horner, Brown, \& Navarrette, 2004; Madrid, Pennington, Brown \& Wolfe, 2011).

This study proposes to study in a more thorough fashion the question of the incidence of bonding disruptions with between mothers and their children with asthma. This time there will be a larger sample, and more stringent criteria will used in assigning children to the asthma cohort. Through questions answered by mothers whose children have been said to have asthma, we will be able to decide if the children's respiratory conditions are likely to be attributable to asthma or more likely reflective of another respiratory condition such as vocal cord dysfunction or anxiety related hyperventilation (Anbar, 2014).

Detailed Description

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Conditions

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Asthma in Children Anxiety

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Asthma

Mothers of children thought to have asthma

Asthma

Intervention Type OTHER

mothers who have children that have been diagnosed with respiratory issues

Non-asthma

Mothers of children without diagnosed respiratory problems

Non-asthma

Intervention Type OTHER

mothers who have children that do not have a diagnosis of respiratory problems

Interventions

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Asthma

mothers who have children that have been diagnosed with respiratory issues

Intervention Type OTHER

Non-asthma

mothers who have children that do not have a diagnosis of respiratory problems

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Biological mothers of male and female children between 2 and 12 years of age who live with or have contact with their children
* English is the primary language of the biological mother

Exclusion Criteria

* Mothers of children only below 2 or above 12 years of age
* Mothers of children thought to have a chronic health condition other than asthma
* Mothers who have already completed a questionnaire with another child
Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Ran Anbar

OTHER

Sponsor Role lead

Responsible Party

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Ran Anbar

Professor

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Ran D Anbar, MD

Role: PRINCIPAL_INVESTIGATOR

State University of New York - Upstate Medical University

Locations

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SUNY Upstate Medical University

Syracuse, New York, United States

Site Status

Countries

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United States

References

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Anbar, R.D. Functional symptoms in pulmonology: taking your breath away. In: Ran D. Anbar (ed), Functional Symptoms in Pediatric Disease: A Clinical Guide. New York, NY: Springer, 2014; 47-58.

Reference Type BACKGROUND

Anbar RD, Geisler SC. Identification of children who may benefit from self-hypnosis at a pediatric pulmonary center. BMC Pediatr. 2005 Apr 25;5(1):6. doi: 10.1186/1471-2431-5-6.

Reference Type BACKGROUND
PMID: 15850484 (View on PubMed)

Annesi-Maesano I, Moreau D, Strachan D. In utero and perinatal complications preceding asthma. Allergy. 2001 Jun;56(6):491-7. doi: 10.1034/j.1398-9995.2001.056006491.x.

Reference Type BACKGROUND
PMID: 11421892 (View on PubMed)

Feinberg, Steven. Degree of maternal infant bonding and its relationship to pediatric asthma and family environments. Unpublished doctoral dissertation, Professional School of Psychology, San Francisco, 1988.

Reference Type BACKGROUND

Kero J, Gissler M, Gronlund MM, Kero P, Koskinen P, Hemminki E, Isolauri E. Mode of delivery and asthma -- is there a connection? Pediatr Res. 2002 Jul;52(1):6-11. doi: 10.1203/00006450-200207000-00004.

Reference Type BACKGROUND
PMID: 12084840 (View on PubMed)

Klaus, M. H., & Kennen, J. H. Maternal-infant bonding. St. Louis, MO: C. V. Mosby, 1976.

Reference Type BACKGROUND

Klinnert MD, Nelson HS, Price MR, Adinoff AD, Leung DY, Mrazek DA. Onset and persistence of childhood asthma: predictors from infancy. Pediatrics. 2001 Oct;108(4):E69. doi: 10.1542/peds.108.4.e69.

Reference Type BACKGROUND
PMID: 11581477 (View on PubMed)

Kozyrskyj AL, Mai XM, McGrath P, Hayglass KT, Becker AB, Macneil B. Continued exposure to maternal distress in early life is associated with an increased risk of childhood asthma. Am J Respir Crit Care Med. 2008 Jan 15;177(2):142-7. doi: 10.1164/rccm.200703-381OC. Epub 2007 Oct 11.

Reference Type BACKGROUND
PMID: 17932381 (View on PubMed)

Madrid A. Helping children with asthma by repairing maternal-infant bonding problems. Am J Clin Hypn. 2005 Oct-2006 Jan;48(2-3):199-211. doi: 10.1080/00029157.2005.10401517.

Reference Type BACKGROUND
PMID: 16482847 (View on PubMed)

Mantymaa M, Puura K, Luoma I, Salmelin R, Davis H, Tsiantis J, Ispanovic-Radojkovic V, Paradisiotou A, Tamminen T. Infant-mother interaction as a predictor of child's chronic health problems. Child Care Health Dev. 2003 May;29(3):181-91. doi: 10.1046/j.1365-2214.2003.00330.x.

Reference Type BACKGROUND
PMID: 12752609 (View on PubMed)

Nafstad P, Samuelsen SO, Irgens LM, Bjerkedal T. Pregnancy complications and the risk of asthma among Norwegians born between 1967 and 1993. Eur J Epidemiol. 2003;18(8):755-61. doi: 10.1023/a:1025395405101.

Reference Type BACKGROUND
PMID: 12974550 (View on PubMed)

Pennington, D. Events associated with maternal-infant bonding deficits and severity of pediatric asthma. Unpublished doctoral dissertation, Professional School of Psychology, San Francisco, 1991.

Reference Type BACKGROUND

Schwartz, M.P. Incidence of events associated with maternal-infant bonding disturbance in a pediatric population. Unpublished doctoral dissertation, Rosebridge Graduate School, Walnut Creek, 1988.

Reference Type BACKGROUND

Roduit C, Scholtens S, de Jongste JC, Wijga AH, Gerritsen J, Postma DS, Brunekreef B, Hoekstra MO, Aalberse R, Smit HA. Asthma at 8 years of age in children born by caesarean section. Thorax. 2009 Feb;64(2):107-13. doi: 10.1136/thx.2008.100875. Epub 2008 Dec 3.

Reference Type BACKGROUND
PMID: 19052046 (View on PubMed)

Wright RJ, Cohen S, Carey V, Weiss ST, Gold DR. Parental stress as a predictor of wheezing in infancy: a prospective birth-cohort study. Am J Respir Crit Care Med. 2002 Feb 1;165(3):358-65. doi: 10.1164/ajrccm.165.3.2102016.

Reference Type BACKGROUND
PMID: 11818321 (View on PubMed)

Wright RJ, Visness CM, Calatroni A, Grayson MH, Gold DR, Sandel MT, Lee-Parritz A, Wood RA, Kattan M, Bloomberg GR, Burger M, Togias A, Witter FR, Sperling RS, Sadovsky Y, Gern JE. Prenatal maternal stress and cord blood innate and adaptive cytokine responses in an inner-city cohort. Am J Respir Crit Care Med. 2010 Jul 1;182(1):25-33. doi: 10.1164/rccm.200904-0637OC. Epub 2010 Mar 1.

Reference Type BACKGROUND
PMID: 20194818 (View on PubMed)

Other Identifiers

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389127

Identifier Type: -

Identifier Source: org_study_id

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