Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
61 participants
OBSERVATIONAL
2014-05-31
2015-02-28
Brief Summary
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Aspirin is the backbone of antiplatelet therapy in patients after ischemic stroke. However, it is known that there are substantial inter-individual response variabilities to antiplatelet medication. Furthermore, patients with impaired response to aspirin have a significant higher risk of recurrent cerebrovascular events. The investigators have recently shown that co-medication with aspirin and dipyrone in patients with coronary artery disease lead to insufficient antiplatelet effects of aspirin.
The incidence of chronic pain is very high in patients with ischemic stroke. Therefore, in this study the investigators aim to examine, if co-medication of aspirin and dipyrone interaction also occurs in patients after ischemic stroke.
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
* Patients with ischemic stroke and ASS-medication (80-320 mg/day) with/without analgesic comedication
Exclusion Criteria
* cardiogenic shock
18 Years
ALL
No
Sponsors
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Heinrich-Heine University, Duesseldorf
OTHER
Responsible Party
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Klinik für Kardiologie, Pneumologie und Angiologie
Division of Cardiology, Pulmonary Diseases, Vascular Medicine
Principal Investigators
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Amin Polzin, MD
Role: PRINCIPAL_INVESTIGATOR
Klinik für Kardiologie, Pneumologie und Angiologie, Universtiätsklinikum Düsseldorf
Tobias Zeus, MD
Role: STUDY_CHAIR
Klinik für Kardiologie, Pneumologie und Angiologie, Universtiätsklinikum Düsseldorf
Locations
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Division of Cardiology, Pulmonary Disease and Vascular Medicine
Düsseldorf, , Germany
Countries
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References
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Dannenberg L, Erschoff V, Bonner F, Gliem M, Jander S, Levkau B, Kelm M, Hohlfeld T, Zeus T, Polzin A. Dipyrone comedication in aspirin treated stroke patients impairs outcome. Vascul Pharmacol. 2016 Dec;87:66-69. doi: 10.1016/j.vph.2016.06.003. Epub 2016 Jun 11.
Related Links
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Related Info
Other Identifiers
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Stroke
Identifier Type: -
Identifier Source: org_study_id
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