Effects of Transcranial Direct Current Stimulation on Cigarette Addiction

NCT ID: NCT02146014

Last Updated: 2016-06-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-05-31

Study Completion Date

2015-12-31

Brief Summary

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Tobacco addiction is treatable with behavioral and pharmacological means, but results are often less than optimal. Transcranial direct current stimulation is a new non-invasive technique that applies weak electrical currents through the skull and has been shown to alter the excitability of certain brain areas. It is currently being tried in disorders where there is abnormal brain excitability, such as epilepsy and depression. A few studies have also been able to diminish drug craving, suggesting that brain excitability might also be altered in drug addiction.

This study aims at non-invasively changing the excitability of certain brain areas-a procedure called neuromodulation- in order to help smokers quit smoking more easily.

Detailed Description

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Conditions

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Addiction

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Transcranial Direct Current Stimulation

These subjects will receive real transcranial direct current stimulation.

Group Type EXPERIMENTAL

Transcranial Direct Current Stimulation

Intervention Type DEVICE

Transcranial Direct Current Stimulation (tDCS) is a procedure that uses a small battery-driven unit to deliver weak electrical currents (1-2 mA) through the intact scalp. The procedure is painless and is thought to modulate the excitability of the underlying cerebral tissue for hours or days after sessions.

Sham tDCS

These subjects will receive sham transcranial direct current stimulation (placebo)

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type OTHER

Transcranial Direct Current Stimulation (tDCS) is a procedure that uses a small battery-driven unit to deliver weak electrical currents (1-2 mA) through the intact scalp. The procedure is painless and is thought to modulate the excitability of the underlying cerebral tissue for hours or days after sessions.

In the placebo group the current will be off.

Interventions

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Placebo

Transcranial Direct Current Stimulation (tDCS) is a procedure that uses a small battery-driven unit to deliver weak electrical currents (1-2 mA) through the intact scalp. The procedure is painless and is thought to modulate the excitability of the underlying cerebral tissue for hours or days after sessions.

In the placebo group the current will be off.

Intervention Type OTHER

Transcranial Direct Current Stimulation

Transcranial Direct Current Stimulation (tDCS) is a procedure that uses a small battery-driven unit to deliver weak electrical currents (1-2 mA) through the intact scalp. The procedure is painless and is thought to modulate the excitability of the underlying cerebral tissue for hours or days after sessions.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* smokers

Exclusion Criteria

* use of psychoactive drugs
* age above 70
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Brasilia

OTHER

Sponsor Role lead

Responsible Party

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Joaquim Brasil-Neto

Dr.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Raphael Boechat-Barros, MD

Role: PRINCIPAL_INVESTIGATOR

University of Brasilia

Locations

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Hospital Universitário de Brasília- HUB

Brasília, Federal District, Brazil

Site Status

Countries

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Brazil

References

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Vitor de Souza Brangioni MC, Pereira DA, Thibaut A, Fregni F, Brasil-Neto JP, Boechat-Barros R. Effects of Prefrontal Transcranial Direct Current Stimulation and Motivation to Quit in Tobacco Smokers: A Randomized, Sham Controlled, Double-Blind Trial. Front Pharmacol. 2018 Jan 26;9:14. doi: 10.3389/fphar.2018.00014. eCollection 2018.

Reference Type DERIVED
PMID: 29434547 (View on PubMed)

Other Identifiers

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TAB-69168

Identifier Type: -

Identifier Source: org_study_id

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