Risk Factors for Recurrence of Primary Bile Duct Stones

NCT ID: NCT02144493

Last Updated: 2014-05-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

2 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-05-31

Study Completion Date

2014-12-31

Brief Summary

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Recurrent common bile duct stone is one of the risk factors of recurrent cholangitis. However, the exact pathophysiology or mechanism of recurrent cholangitis has not been established. Periampullary diverticulum and narrow angle of common bile duct have been postulated as risk factors of recurrent common bile duct stone. The aim of this study was to evaluate the association between periampullary dierticulum, angle of common bile duct and recurrent common bile duct stone.

Detailed Description

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Recurrent common bile duct stone is one of the risk factors of recurrent cholangitis. However, the exact pathophysiology or mechanism of recurrent cholangitis has not been established. Periampullary diverticulum and narrow angle of common bile duct have been postulated as risk factors of recurrent common bile duct stone. The aim of this study was to evaluate the association between periampullary dierticulum, angle of common bile duct and recurrent common bile duct stone.

This study is patient-control setting study. Firstly, from July 2007 through February 2014, all the patients who were performed ERCP will be enrolled. The inclusion criteria is the patients with common bile duct stone. The exclusion criteria is patients with biliary stenosis, PSC, retained GB stone, or who were lost to follow-up. The main outcome is the association between periampullary diverticulum, common bile duct angle, and recurrent CBD stone. This will be evaluated by univariate and multivariate analyses.

Conditions

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Common Bile Duct Stones

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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Patients with recurrent CBD stone

The existence of periampullary diverticulum

Intervention Type OTHER

Periampullary diverticulum has been postulated as risk factor of recurrent CBD stone.

CBD angle

Intervention Type OTHER

Narrow CBD angle has been postulated as risk factor for the development of recurrent CBD stone

Patients without recurrent CBD stone

The existence of periampullary diverticulum

Intervention Type OTHER

Periampullary diverticulum has been postulated as risk factor of recurrent CBD stone.

CBD angle

Intervention Type OTHER

Narrow CBD angle has been postulated as risk factor for the development of recurrent CBD stone

Interventions

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The existence of periampullary diverticulum

Periampullary diverticulum has been postulated as risk factor of recurrent CBD stone.

Intervention Type OTHER

CBD angle

Narrow CBD angle has been postulated as risk factor for the development of recurrent CBD stone

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients who were performed ERCP due to CBD stone or calculous cholangitis

Exclusion Criteria

* Patients with biliary stricture, PSC, retained GB stone, or who were lost to follow-up.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Chuncheon Sacred Heart Hospital

OTHER

Sponsor Role lead

Responsible Party

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Jai Hoon Yoon

Professor Jai Hoon Yoon

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jai Hoon Yoon, M.D..Ph.D.

Role: STUDY_CHAIR

Hallym University College of Medicine, Chuncheon Sacred Heart hospital

Locations

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Chuncheon Sacred Heart Hospital

Chuncheon, Gangwon-do, South Korea

Site Status RECRUITING

Countries

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South Korea

Central Contacts

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Jai Hoon Yoon, M.D.,Ph.D.

Role: CONTACT

+821032553957

Facility Contacts

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Young Hee Lee

Role: primary

82332405128

References

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Keizman D, Shalom MI, Konikoff FM. An angulated common bile duct predisposes to recurrent symptomatic bile duct stones after endoscopic stone extraction. Surg Endosc. 2006 Oct;20(10):1594-9. doi: 10.1007/s00464-005-0656-x. Epub 2006 Jul 20.

Reference Type BACKGROUND
PMID: 16858527 (View on PubMed)

Katsinelos P, Chatzimavroudis G, Tziomalos K, Zavos C, Beltsis A, Lazaraki G, Terzoudis S, Kountouras J. Impact of periampullary diverticula on the outcome and fluoroscopy time in endoscopic retrograde cholangiopancreatography. Hepatobiliary Pancreat Dis Int. 2013 Aug;12(4):408-14. doi: 10.1016/s1499-3872(13)60063-6.

Reference Type BACKGROUND
PMID: 23924499 (View on PubMed)

Panteris V, Vezakis A, Filippou G, Filippou D, Karamanolis D, Rizos S. Influence of juxtapapillary diverticula on the success or difficulty of cannulation and complication rate. Gastrointest Endosc. 2008 Nov;68(5):903-10. doi: 10.1016/j.gie.2008.03.1092. Epub 2008 Jul 16.

Reference Type BACKGROUND
PMID: 18635174 (View on PubMed)

Other Identifiers

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ChuncheonSHH YJH-1

Identifier Type: OTHER

Identifier Source: secondary_id

YJH-1

Identifier Type: -

Identifier Source: org_study_id

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