Knee Pain Phenotypes in the Community Study

NCT ID: NCT02098070

Last Updated: 2017-08-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

40000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-09-30

Study Completion Date

2018-09-30

Brief Summary

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The focus of the study is to determine the prevalence and variance of self-reported knee pain characteristics in a community-derived sample of adults aged 40 years and over. It will also identify characteristics such as structural changes of osteoarthritis of the knee as well as physiological parameters and blood and urine biomarkers.

Detailed Description

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Number of participants:

Part I: questionnaire to 40,000 people aged 40 years and over (giving an expected 10,000 respondents) Part II: 400 participants.

Conditions

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Knee Osteoarthritis

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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Knee Pain Population

Participants who have responded to the questionnaire with self-reported pain.

No interventions assigned to this group

Non-Knee Pain Population

Participants who have responded to the questionnaire, no self-reported pain.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Aged 40 years and over

Exclusion Criteria

* Inability to give informed consent
* Terminal or mental illness
* Pregnant women
Minimum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Arthritis Research UK

OTHER

Sponsor Role collaborator

University of Nottingham

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Michael Doherty, MD

Role: PRINCIPAL_INVESTIGATOR

University of Nottingham

Locations

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Academic Rheumatology

Nottingham, Nottinghamshire, United Kingdom

Site Status

Countries

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United Kingdom

References

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Swain S, Fernandes GS, Sarmanova A, Valdes AM, Walsh DA, Coupland C, Doherty M, Zhang W. Comorbidities and use of analgesics in people with knee pain: a study in the Nottingham Knee Pain and Health in the Community (KPIC) cohort. Rheumatol Adv Pract. 2022 Jun 15;6(2):rkac049. doi: 10.1093/rap/rkac049. eCollection 2022.

Reference Type DERIVED
PMID: 35784017 (View on PubMed)

Fernandes GS, Parekh SM, Moses J, Fuller CW, Scammell B, Batt ME, Zhang W, Doherty M. Depressive symptoms and the general health of retired professional footballers compared with the general population in the UK: a case-control study. BMJ Open. 2019 Sep 8;9(9):e030056. doi: 10.1136/bmjopen-2019-030056.

Reference Type DERIVED
PMID: 31501119 (View on PubMed)

Fernandes GS, Valdes AM, Walsh DA, Zhang W, Doherty M. Neuropathic-like knee pain and associated risk factors: a cross-sectional study in a UK community sample. Arthritis Res Ther. 2018 Sep 27;20(1):215. doi: 10.1186/s13075-018-1717-6.

Reference Type DERIVED
PMID: 30261907 (View on PubMed)

Fernandes GS, Sarmanova A, Warner S, Harvey H, Akin-Akinyosoye K, Richardson H, Frowd N, Marshall L, Stocks J, Hall M, Valdes AM, Walsh D, Zhang W, Doherty M. Knee pain and related health in the community study (KPIC): a cohort study protocol. BMC Musculoskelet Disord. 2017 Sep 21;18(1):404. doi: 10.1186/s12891-017-1761-4.

Reference Type DERIVED
PMID: 28934932 (View on PubMed)

Other Identifiers

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14018

Identifier Type: -

Identifier Source: org_study_id

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