Tolerance and Utilization of Polydextrose, Inulin, and Soluble Corn Fiber
NCT ID: NCT02091349
Last Updated: 2014-05-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
25 participants
INTERVENTIONAL
2010-07-31
2012-07-31
Brief Summary
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Detailed Description
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The object of this study are first to determine the tolerance of soluble fibers polydextrose, inulin and nutriose when provided as supplemental fiber to an existing diet. The second objective is to determine the utilization of polydextrose and nutriose through analyses of fecal samples of fermentative end-products and shifts in microbial populations.
Conditions
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Study Design
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RANDOMIZED
CROSSOVER
BASIC_SCIENCE
DOUBLE
Study Groups
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Group A- placebo
control- snack bar or muffin containing no fiber
polydextrose
polydextrose- 7, 14, or 21 grams/day 3X3 latin square with 3 periods
soluble corn fiber
nutirose- 7, 14, or 21 grams/day
Group B- polydextrose
polydextrose- randomly bonded polysaccharide of glucose which is poorly digested in small intestine
polydextrose
polydextrose- 7, 14, or 21 grams/day 3X3 latin square with 3 periods
soluble corn fiber
nutirose- 7, 14, or 21 grams/day
Group C- soluble corn fiber
Soluble corn fiber made from corn starch and contains oligosaccharides with random glyucosyl bonds and may contain minor amounts of monosaccharides
polydextrose
polydextrose- 7, 14, or 21 grams/day 3X3 latin square with 3 periods
soluble corn fiber
nutirose- 7, 14, or 21 grams/day
Interventions
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polydextrose
polydextrose- 7, 14, or 21 grams/day 3X3 latin square with 3 periods
soluble corn fiber
nutirose- 7, 14, or 21 grams/day
Eligibility Criteria
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Inclusion Criteria
* free of metabolic and gastrointestinal disease
Exclusion Criteria
* presence of metabolic or gastrointestinal diseases
20 Years
40 Years
MALE
Yes
Sponsors
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University of Illinois at Urbana-Champaign
OTHER
Responsible Party
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Principal Investigators
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George Fahey, Jr, PhD
Role: PRINCIPAL_INVESTIGATOR
UIUC
References
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Holscher HD, Caporaso JG, Hooda S, Brulc JM, Fahey GC Jr, Swanson KS. Fiber supplementation influences phylogenetic structure and functional capacity of the human intestinal microbiome: follow-up of a randomized controlled trial. Am J Clin Nutr. 2015 Jan;101(1):55-64. doi: 10.3945/ajcn.114.092064. Epub 2014 Nov 12.
Other Identifiers
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09491
Identifier Type: -
Identifier Source: org_study_id
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