MedDataX Logo

Clinical Effects of Soluble Dietary Fiber Supplementation

NCT ID: NCT02194972

Last Updated: 2018-08-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

80 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-05-31

Study Completion Date

2012-10-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to investigate the effect of pectin, a kind of soluble dietary fiber, on colonic transit time, clinical symptoms and the gut microbiota in adults with slow-transit constipation.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Evaluating the Synergism of Soluble Dietary Fiber With Fecal Microbiota Transplantation in Slow Transit Constipation

NCT02291354

Slow Transit Constipation
UNKNOWN PHASE2

Efficacy and Safety of Fecal Microbiota Transplantation for Slow Transit Constipation

NCT02526849

Slow Transit Constipation
UNKNOWN PHASE2

CMTS4520 for Chronic Constipation in Adults

NCT06832137

Constipation
NOT_YET_RECRUITING PHASE1/PHASE2

Freeze-dried vs Fresh Fecal Microbiota Transplantation in Patients With Slow Transit Constipation

NCT02676388

Slow Transit Constipation
UNKNOWN PHASE2

Effect of Fecal Microbiota Transplantation in Slow Transit Constipation

NCT02301221

Slow Transit Constipation
UNKNOWN PHASE2

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Patients were randomized to receive either pectin or placebo. Treatment consisted of 4 weeks supplementation with pectin (fiber group) or placebo. We evaluated the colonic transit time, constipation symptoms and fecal bacterial population in two groups.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Hypomotility Constipation

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

soluble dietary fiber

pectin, a kind of soluble dietary fiber

Group Type EXPERIMENTAL

Pectin

Intervention Type DRUG

pectin （Andeli Ltd. Yantai, China）, 24g/d for 4weeks

Placebo

Placebo

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Pectin

pectin （Andeli Ltd. Yantai, China）, 24g/d for 4weeks

Intervention Type DRUG

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

soluble dietary fiber

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* All patients(age≧18y)
* Admitted for slow-transit constipation were considered eligible

Exclusion Criteria

* Mental disorders
* Cancer
* Inflammatory bowel disease
Minimum Eligible Age

18 Years

Maximum Eligible Age

78 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Nanjing PLA General Hospital

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Gao Tao

Nanjing PLA General Hospital

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Tao Gao, M.D.

Role: PRINCIPAL_INVESTIGATOR

Nanjing PLA General Hospital

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

2011NLY42

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Trial on Short-chain Fructooligosaccharides, Microbiota, and Constipation in Adults
NCT02140749 COMPLETED NA
CMTS4520-Assisted Washed Microbiota Transplantation for Chronic Constipation in Adults
NCT06832176 NOT_YET_RECRUITING PHASE1/PHASE2
Efficacy and Safety of Plecanatide Comparing With Placebo in the Treatment of Functional Constipation
NCT05151328 COMPLETED PHASE3
Dose-ranging Efficacy of Polydextrose Supplement on Colonic Transit Time and Symptoms in Adults With Functional Constipation
NCT02314936 COMPLETED PHASE2
This Study Aims to Evaluate the Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Properties and Food Effect of IN-114199 in Healthy Participants
NCT06736912 NOT_YET_RECRUITING PHASE1
Fibers and Gut Health
NCT02234518 COMPLETED NA
Fiber and Water Improve Bowel Habit in Humans
NCT02838849 COMPLETED PHASE1/PHASE2
Constipation Fiber Trial
NCT02193997 COMPLETED NA
Clinical Study of Resistant Starch in Improving Constipation
NCT06292949 RECRUITING NA
Efficacy and Safety Study of the Effect of Dose-Titration of Prucalopride for The Treatment of Chronic Constipation
NCT00577018 COMPLETED PHASE3
Dose-Responsive Effect of Polydextrose on Whole Gut Transit Time
NCT01540669 TERMINATED NA
Comparison of PolyethyleneGlycol and Placebo for Relief of Constipation From Constipating Medications
NCT00153127 COMPLETED PHASE4
Improving Constipation by Stimulating Fiber Intake Using Personalized Dietary Advice
NCT04457791 COMPLETED NA
Chronic Ingestion of Fructooligosaccharide and Psyllium on Intestinal Transit in Women With Functional Constipation: A Randomized Crossover Trial
NCT07202481 RECRUITING NA
Effect of Methylcellulose or Psyllium on Fermentation of inUlin Assessed USing MRI
NCT06291272 COMPLETED NA
Effect and Safety of Polyethylene Glycol Combined With Linaclotide on Colon Cleansing for Patients With Chronic Constipation
NCT05137145 UNKNOWN NA
Effect of Polydextrose on Fecal Bulk and Bowel Function in Mildly Constipated Subjects
NCT05309837 COMPLETED NA
Effect of Naloxegol on Gastric, Small Bowel, and Colonic Transit in Healthy Subjects
NCT02737059 COMPLETED PHASE1
Prebiotic Fructans Effect on 1-3 Years Constipated Children's Bowel Habits
NCT03941925 UNKNOWN NA
Study of NGM282 in Subjects With Functional Constipation and Healthy Individuals
NCT02649062 COMPLETED PHASE1/PHASE2
Washed Microbiota Transplantation for Chronic Constipation in Adults
NCT06106685 RECRUITING PHASE1/PHASE2
Fecal Microbiota Transplantation for Constipation
NCT03308461 COMPLETED NA
Pilot Study of the Effect of Fructans on Fermentation in the Colon & Transit
NCT01963364 COMPLETED NA
Dietary Supplementation Effects on Bowel Movement Frequency and Intestinal Biological Markers in Seniors Presenting Slowed Intestinal Transit
NCT04304170 COMPLETED NA
Fiber Fermentation Kinetics Inside the Gut, and Utilization of Bacterial Metabolites
NCT04013607 COMPLETED NA