Intracorporeal Versus Extracorporeal Morcellation: Clinical Efficacy and Safety Outcomes

NCT ID: NCT02086435

Last Updated: 2015-04-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

93 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-03-31

Study Completion Date

2015-04-30

Brief Summary

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The aim of this study protocol will be to compare the technique of intracorporeal morcellation using reusable electronic device (standard technique) with a technique of removal "protected" by endobag and extracorporeal myoma morcellation with cold scissors and scalpel blade or with power morcellator used inside the bag itself.

Detailed Description

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Conditions

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Uterine Myoma

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Extracorporeal morcellation

Extracorporeal morcellation in which patients are treated with "protected" removal by endobag and extracorporeal myoma morcellation with cold scissors and scalpel blade or with power morcellator used inside the bag itself

Group Type EXPERIMENTAL

Extracorporeal morcellation

Intervention Type PROCEDURE

patients treated with "protected" removal by endobag and extracorporeal myoma morcellation with cold scissors and scalpel blade or with power morcellator used inside the bag itself

Intracorporeal morcellation

Intracorporeal morcellation patients treated with standard intracorporeal morcellation, using reusable electronic device

Group Type ACTIVE_COMPARATOR

Intracorporeal morcellation

Intervention Type PROCEDURE

patients treated with standard intracorporeal morcellation, using reusable electronic device

Interventions

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Extracorporeal morcellation

patients treated with "protected" removal by endobag and extracorporeal myoma morcellation with cold scissors and scalpel blade or with power morcellator used inside the bag itself

Intervention Type PROCEDURE

Intracorporeal morcellation

patients treated with standard intracorporeal morcellation, using reusable electronic device

Intervention Type PROCEDURE

Other Intervention Names

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protected morcellation morcellation in endobag Power morcellation Standard intracorporeal morcellation

Eligibility Criteria

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Inclusion Criteria

* Patients undergoing laparoscopy for uterine myomas with international guidelines surgical indications
* Presence of at least one uterine myoma larger than 4 cm
* Aged between 18 and 40 years

Exclusion Criteria

* Presence of uterine neoformations suspicious for malignancy
* Medical major disorders associated
* Acute or chronic psychiatric disorders
* Ascertained Premenstrual syndrome
* Use of drugs that can affect cognitive ability or state of consciousness and alertness during the last six months prior to enrollment
* Presence of calcified fibroids ultrasound examination
* Presence of adnexal lesions
* Detection of a pattern of endometrial hyperplasia with atypia determined in the course endometrial biopsy performed for abnormal uterine bleeding
* Abnormal PAP test
* Positive Pregnancy Test
* Previous use of laparoscopic surgery increased
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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University Magna Graecia

OTHER

Sponsor Role lead

Responsible Party

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Fulvio Zullo

Full Professor Obstetric Gynecology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Fulvio Zullo

Role: PRINCIPAL_INVESTIGATOR

Magna Graecia University of Catanzaro

Locations

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Chair of Obstetrics and Gynecology - University division - UMG

Catanzaro, CZ, Italy

Site Status

Countries

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Italy

References

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Venturella R, Rocca ML, Lico D, La Ferrera N, Cirillo R, Gizzo S, Morelli M, Zupi E, Zullo F. In-bag manual versus uncontained power morcellation for laparoscopic myomectomy: randomized controlled trial. Fertil Steril. 2016 May;105(5):1369-1376. doi: 10.1016/j.fertnstert.2015.12.133. Epub 2016 Jan 19.

Reference Type DERIVED
PMID: 26801067 (View on PubMed)

Other Identifiers

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SafeMorcellation

Identifier Type: -

Identifier Source: org_study_id

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