Changes of Dendritic Cells in Acute Lung Injury

NCT ID: NCT02083393

Last Updated: 2015-05-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

19 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-06-30

Study Completion Date

2014-12-31

Brief Summary

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To observe changes of circulating and tissue dendritic cells in acute lung injury,including invasive aspergillosis pneumonia

Detailed Description

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Change of circulating and tissular dendritic cells of patients with acute lung injury was still unclear, we used a flow cytometry-based assay to quantify circulating and tissular DCs and their HLA-DR surface expression at the time of diagnosis and during the first week of evolution in patients with acute lung injury, and healthy people as controls.

Conditions

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Acute Lung Injury

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients with acute lung injury

Patients with sepsis induced acute lung injury

No interventions assigned to this group

Postsurgery patients

Postsurgery patients without acute lung injury and sepsis

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Sepsis induced acute lung injury

Exclusion Criteria

* Younger than 18-year-old
* Pregnancy
* Cancer or organ transplant
* Asthma
* COPD
* Heart Failure
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Southeast University, China

OTHER

Sponsor Role lead

Responsible Party

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Jingyuan,Xu

Zhongda Hospital

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Haibo Qiu, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Southeast University

Locations

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Zhongda Hospital Southeast University

Nanjing, Jiangsu, China

Site Status

Countries

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China

Other Identifiers

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SoutheastUChina2011ZDllKY04

Identifier Type: -

Identifier Source: org_study_id

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