Acupuncture for Obesity on Serum Metabolic Parameters

NCT ID: NCT02066090

Last Updated: 2017-11-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-03-31

Study Completion Date

2016-02-29

Brief Summary

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This research is planned to build a basis about the effect of acupuncture on serum metabolic parameters in pre-menopausal obese women with economic evaluation.

Detailed Description

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It is consisted with two sub research.

First, clinical research to assess the effect of acupuncture for obesity on serum metabolic parameters will be processed with randomized, patient-assessor blinding, and sham-acupuncture controlled study design. 120 subjects would be collected and divided into two groups(experimental and placebo, 60 subjects each). Experimental group will undergo with real acupuncture treatment(manual acupuncture + electroacupuncture) twice a week, for 6 weeks. The effect on serum metabolic parameters will be assessed at 0 and 6 weeks.

Second is qualitative research to make a basis through the evaluation of economic efficacy and patients' satisfaction with acupuncture treatment for obesity.

Conditions

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Obesity

Keywords

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acupuncture obesity metabolomics

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Real acupuncture

manual acupuncture + electroacupuncture, twice a week, for 6 weeks

Group Type EXPERIMENTAL

Real acupuncture

Intervention Type DEVICE

manual acupuncture (bilateral LI4, LI11, SP6, ST25, ST28, ST36) + electroacupuncture (middle CV6, CV12), twice a week, for 6 weeks

common approaches for the treatment of obesity used by doctors of Korean medicine in Korea today

Sham acupuncture

sham acupuncture + placebo acupuncture without electrical stimulation, twice a week, for 6 weeks

Group Type SHAM_COMPARATOR

Sham acupuncture

Intervention Type DEVICE

sham acupuncture (bilateral LI4, LI11, SP6, ST25, ST28, ST36) + placebo acupuncture without electrical stimulation (middle CV6, CV12), twice a week, for 6 weeks

sham acupuncture (0.25mm diameter x 40mm length, stainless steel, Acuprime, UK) as control for manual acupuncture (0.25mm diameter x 40mm length, stainless steel, Dongbangacupuncture Inc., Korea)

placebo acupuncture without electrical stimulation as control for electroacupuncture (0.25mm diameter x 90mm length, stainless steel, Dongbangacupuncture Inc., Korea)

Interventions

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Real acupuncture

manual acupuncture (bilateral LI4, LI11, SP6, ST25, ST28, ST36) + electroacupuncture (middle CV6, CV12), twice a week, for 6 weeks

common approaches for the treatment of obesity used by doctors of Korean medicine in Korea today

Intervention Type DEVICE

Sham acupuncture

sham acupuncture (bilateral LI4, LI11, SP6, ST25, ST28, ST36) + placebo acupuncture without electrical stimulation (middle CV6, CV12), twice a week, for 6 weeks

sham acupuncture (0.25mm diameter x 40mm length, stainless steel, Acuprime, UK) as control for manual acupuncture (0.25mm diameter x 40mm length, stainless steel, Dongbangacupuncture Inc., Korea)

placebo acupuncture without electrical stimulation as control for electroacupuncture (0.25mm diameter x 90mm length, stainless steel, Dongbangacupuncture Inc., Korea)

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* volunteers through announcements and advertisements
* premenopausal adult women (19 years of age or more)
* clinical diagnosis of obesity (Body mass index: 25 kg/m2 or more)

Exclusion Criteria

* previously or currently having endocrine disease such as hypothyroidism or Cushing's syndrome, heart disease, lung disease, diabetes, malignant tumor, cholelithiasis, severe kidney impairment, severe liver impairment, anorexia nervosa or hyperorexia
* experience of taking medicines which might affect body weight and the concentration of serum metabolic parameters such as anorectic, laxative, oral steroid, thyroid hormone, amphetamine, cyproheptadine, phenothiazine, or medicines affecting absorption, metabolism, and excretion in the past 3 months
* experience of taking beta-blocker or diuretic for the treatment of hypertension in the past 3 months
* surgical treatment for the treatment of obesity
* currently or might be pregnant or breast-feeding
* experience of taking other experimental medicines in the past month
* weight loss of 10% or more of previous body weight in the past 6 months
* who stopped smoking in the past 3 months or who have irregular smoking habit
* pacemaker
* currently receiving any treatment for obesity
* other inadequate subjects assessed by the study investigators
Minimum Eligible Age

19 Years

Maximum Eligible Age

55 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Kyung Hee University Hospital at Gangdong

OTHER

Sponsor Role lead

Responsible Party

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Mi-Yeon Song

Professor, K.M.D., Ph.D.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mi-Yeon Song, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

Department of Rehabilitation Medicine of Korean Medicine, Kyung Hee University Gangdong Hospital

Locations

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Kyung Hee University Korean Medicine Hospital at Gangdong

Seoul, , South Korea

Site Status

Countries

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South Korea

References

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Kim KW, Shin WC, Choi MS, Cho JH, Park HJ, Yoo HH, Song MY. Effects of acupuncture on anthropometric and serum metabolic parameters in premenopausal overweight and obese women: a randomized, patient- and assessor-blind, sham-controlled clinical trial. Acupunct Med. 2021 Feb;39(1):30-40. doi: 10.1177/0964528420912259. Epub 2020 Apr 17.

Reference Type DERIVED
PMID: 32299241 (View on PubMed)

Kim KW, Yoo HH, Cho JH, Yang YC, Kim JI, Kim SY, Park JY, Park HJ, Song MY. Effects of acupuncture on serum metabolic parameters in premenopausal obese women: study protocol for a randomized controlled trial. Trials. 2015 Aug 4;16:327. doi: 10.1186/s13063-015-0867-y.

Reference Type DERIVED
PMID: 26238111 (View on PubMed)

Other Identifiers

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KHNMCOH 2013-01-020

Identifier Type: -

Identifier Source: org_study_id