Transversus Abdominis Plane Block in Pediatrics: Volume or Concentration ?

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

70 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-11-30

Study Completion Date

2015-11-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The transversus abdominis plane (TAP) block provide a local anesthesia drug diffusion between the transverse abdominis muscle and the internal oblique muscle. TAP block reaches the anterior rami of spinal nerves from T7 to L1 involved in the innervation of homolateral abdominal wall. The transversus abdominis plane block has shown promise for perioperative analgesia, but data on the optimal dose regimen are limited.Following previous research of optimal dose of local anesthesic solution, the investigators aim to evaluate if a "volume effect" would lead to a better diffusion of the local anesthesic solution to the overall nervous roots. The local anesthesia drug choosen is levobupivacaine with a unique posology of 0,4 mg/kg (either 0,2 ml/kg of 0,2% levobupivacaine for "small volume" group or 0,4 ml/kg of 0,1% levobupivacaine for "high volume" group).With the same dose of levobupivacaine, this study aims to assess the impact of volume effect on analgesia efficiency as well as the security as after ultrasound TAP block on one to five years' old children who undergo a peritoneal-vaginal duct surgery.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Transversus Abdominis Plane Block for Pain Relieve in Children Undergoing Groin Surgery

NCT00970086

Postoperative Pain Reaction; Anesthesia

TERMINATED PHASE4

TAP Block Versus Local Anesthesia Wound Infiltration for Postoperative Pain Relief After Appendicectomy in Children

NCT04969133

Appendicitis Acute Pediatrics Analgesia

COMPLETED NA

TAPB vs. Caudal for Lower Abdominal Surgery in Children: A Double-Blinded Randomized Controlled Trial

NCT02160821

Anesthesia, Recovery Period

COMPLETED PHASE4

Blood Bupivacaine Concentration After Regional Block Applications in Pediatric Patients

NCT07256535

Blood Bupivacaine Concentration

NOT_YET_RECRUITING NA

Posterior Quadratus Lumborum Block Using 0.125% Versus 0.25% Bupivacaine for Analgesia in Children Undergoing LPEC

NCT04998071

Postoperative Pain

UNKNOWN NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Inguinal or Ovarian Hernia Hydrocele Cord Kyst Local Analgesia Block One to Five Years

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Blinding Strategy

SINGLE

Participants

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Small volume

Local analgesia by one injection of 0,2 ml/kg of 0,2% lévobupivacaine

Group Type EXPERIMENTAL

Injection of 0,2 ml/kg of 0,2% levobupivacaine for small volume group

Intervention Type DRUG

Ultrasound guided administration of 0,2 ml/kg of 0,2% lévobupivacaine in the plane between the internal oblique and transversus abdominis muscles

High volume

Local analgesia by one injection of 0,4 ml/kg of 0,1% lévobupivacaine

Group Type EXPERIMENTAL

Injection of 0,4 ml/kg of 0,1% lévobupivacaine for high volume group

Intervention Type DRUG

Ultrasound guided administration of 0,4 ml/kg of 0,1% lévobupivacaine in the plane between the internal oblique and transversus abdominis muscles

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Injection of 0,2 ml/kg of 0,2% levobupivacaine for small volume group

Ultrasound guided administration of 0,2 ml/kg of 0,2% lévobupivacaine in the plane between the internal oblique and transversus abdominis muscles

Intervention Type DRUG

Injection of 0,4 ml/kg of 0,1% lévobupivacaine for high volume group

Ultrasound guided administration of 0,4 ml/kg of 0,1% lévobupivacaine in the plane between the internal oblique and transversus abdominis muscles

Intervention Type DRUG

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Hospitalisation in ambulatory surgery and anesthesia unit for surgery of inguinal hernia or ovarian hernia or hydrocele or cord kyst
* Overall status: ASA I-II
* Aged from 1 to 5 years
* Informed consent

Exclusion Criteria

* Coagulation trouble
* Infection on ponction zone
* Local anesthesia drug or nonsteroidal anti inflammatory intolerance
* Cardiac/Renal/hepacticdysfunction
* Hemorrage, digestive perforation history

Minimum Eligible Age

1 Year

Maximum Eligible Age

5 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No