Non-Enhanced Magnetic Resonance Angiography With the t-SLIP Technique

NCT ID: NCT02032940

Last Updated: 2023-04-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-04-30

Study Completion Date

2020-04-30

Brief Summary

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The purpose of the study is to create MR images using an investigative technique called pulse sequences with new computer software programs. The sequence will allow us to image vessels without injecting contrast agents.

Detailed Description

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The t-SLIP Investigational Study Sequences are designed to compare t-SLIP to standard MR contrast enhanced imaging techniques to establish the diagnosic benefits of t-SLIP compared to contrast enhanced MR techniques. The t-SLIP Investigational Study Sequences will be used for vascular MRI Imaging including, but no limited to, MRA of the renal, mesenteric, abdominal aortic, iliac and femoral arteries. We will be targeting all adult patients undergoing standard body MRA examinations without anesthesia.

The time spatial labeling inversion pulse (t-SLIP) technique is used for non contrast enhanced MR angiography imaging. It produces bright blood spin labeling images by using a single acquisition with a combination of a spatially nonselective inversion pulse and a spatially selective inversion pulse. The nonselective pulse inverts the magnetization of the entire imaging area. The spatially selective pulse, applied upstream of the arteries of interest, reverts those protons to full magnetization. A pre defined time delay between tagging and imaging allows the tagged spins to reach the imaging region and suppresses background tissue within the imaging region to some extent.

Conditions

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Focus of Study is MRI

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Standard Sequence Imaging MRI

Patients requiring MRI. All Comers accepting study participation.

No interventions assigned to this group

Additional Pulse Sequence Increased

Patients requiring MRI. All comers accepting study participation and the run of additional pulse sequences during MRI procedure.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* All patients that are considered candidates and scheduled for standard contrast enhanced MRA can be included in the study.

Exclusion Criteria

* Patients that can not undergo standard MRA
Minimum Eligible Age

18 Years

Maximum Eligible Age

95 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Miami Cardiac and Vascular Institute

OTHER

Sponsor Role lead

Responsible Party

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Constantino Pena, MD

Constantino Pena, MD. Medical Director of Vascular Imaging

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Constantino Pena, MD

Role: PRINCIPAL_INVESTIGATOR

Baptist Cardiac and Vascular Institute

Locations

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Baptist Cardiac and Vascular Institute

Miami, Florida, United States

Site Status

Miami Cardiac and Vascular Institute

Miami, Florida, United States

Site Status

Countries

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United States

Other Identifiers

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2013-020

Identifier Type: -

Identifier Source: org_study_id

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