Observational Prospective Study of the Predicted Value of Immature Thrombocytes Counts in Three Different Groups of Critically Ill Patients

NCT ID: NCT02016859

Last Updated: 2013-12-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-01-31

Study Completion Date

2014-11-30

Brief Summary

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Immature Platelet Fraction (IPF) is a new value in CBC blood tests Recent Studies showed that this value may be another prognostic factor in critically ill patients such as those admitted to ICU, or those with neutropenic Fever.

The purpose of the study is to check if the IPF may be used as a prognostic Factor in these patients

Detailed Description

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In this study we have 3 groups of patients

* Patients admitted to ICU
* Patients admitted with neutropenic fever
* Patients admitted with hip fractures it is a prospective study, not interventional, we'll take blood samples of these patients including CBC count eith IPF and other inflammation markers such as CRP and we'll compare CRP to IPF in addition to clinical follow-up of the patient till discharge.

At the end of this study we'll compare the efficacy of IPF as a prognostic Factor in these patients

Conditions

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Critically Ill Patients Neutropenic Fever Patients Patients With Hip Fractures

Keywords

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IPF Immature platelet fraction ICU neutropenic fever hip fracture critically ill

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Critically ill patients admitted to ICU

those patients who are admitted to ICU with multiorgan failure/injury

Immature Platelet Fraction

Intervention Type OTHER

Neutropinc Fever patients

admitted to ER, haemato-oncology or oncology

Immature Platelet Fraction

Intervention Type OTHER

Patients of Hip's Fracture

admitted to orthopedic departement

Immature Platelet Fraction

Intervention Type OTHER

Interventions

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Immature Platelet Fraction

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

\- Admission to hospital blood sample is taken between 24:00 pm till 15:00 pm

Exclusion Criteria

* blood sample is taken after 15:00 pm in the first day of admission during the week
* blood sample is taken on weekend: thursday 15:00 pm till saturday 24:00 pm
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Dr. Yishai Ofran

OTHER

Sponsor Role lead

Responsible Party

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Dr. Yishai Ofran

Doctor

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Rambam Health care campus

Haifa, , Israel

Site Status

Countries

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Israel

Central Contacts

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Yishai Ofran, Doctor

Role: CONTACT

Phone: 009720502061524

Email: [email protected]

Doaa Okasha, doctor

Role: CONTACT

Phone: 009720502062701

Email: [email protected]

References

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Di Mario A, Garzia M, Leone F, Arcangeli A, Pagano L, Zini G. Immature platelet fraction (IPF) in hospitalized patients with neutrophilia and suspected bacterial infection. J Infect. 2009 Sep;59(3):201-6. doi: 10.1016/j.jinf.2009.07.007. Epub 2009 Jul 18.

Reference Type RESULT
PMID: 19647322 (View on PubMed)

De Blasi RA, Cardelli P, Costante A, Sandri M, Mercieri M, Arcioni R. Immature platelet fraction in predicting sepsis in critically ill patients. Intensive Care Med. 2013 Apr;39(4):636-43. doi: 10.1007/s00134-012-2725-7. Epub 2012 Oct 24.

Reference Type RESULT
PMID: 23093245 (View on PubMed)

Other Identifiers

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IPF-2013-Rambam

Identifier Type: -

Identifier Source: org_study_id