Intra Testicular Artery Injection of Bone Marrow Stem Cell in Management of Azoospermia

NCT ID: NCT02008799

Last Updated: 2015-04-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-01-31

Study Completion Date

2016-12-31

Brief Summary

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Azoospermia due to low sperm production (non-obstructive azoospermia) affects approximately 1% of the male population and 10% of men who seek fertility evaluation. Testis biopsy reveals that these men have Sertoli cell-only pattern, maturation arrest, or hypospermatogenesis. Until recently, it was assumed that men with non-obstructive azoospermia were untreatable. Indeed, these patients were often referred to as being "sterile" or having "testicular failure." We start to use stem cell in treatment of such patients by injecting the stem cell at the testis and the testicular artery in one group and at the testis only in other group

Detailed Description

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Conditions

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Azoospermia

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

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Bone marrow stem cell injection

through special butterfly inject stem cell in testicular artery and inside tubules

Group Type EXPERIMENTAL

Bone marrow stem cell injection

Intervention Type PROCEDURE

Injection should be in testis and testicular artery

Interventions

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Bone marrow stem cell injection

Injection should be in testis and testicular artery

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

\- Azoospermia

Exclusion Criteria

\- Absent or surgical removed testes
Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Man Clinic for Andrology, Male Infertility and Sexual Dysfunction

OTHER

Sponsor Role lead

Responsible Party

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Khaled Abdulmoneim Gadalla

Prof Dr

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Khaled A Gadalla, MD

Role: PRINCIPAL_INVESTIGATOR

Man Clinic

Locations

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Man Clinic

Cairo, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Khaled A Gadalla, MD

Role: CONTACT

20222725025

Facility Contacts

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Khaled A Gadalla, MD

Role: primary

20222725025

Other Identifiers

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SCA2013

Identifier Type: -

Identifier Source: org_study_id

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