The Fluid Translation of Research Into Practice Study

NCT ID: NCT02002013

Last Updated: 2015-03-11

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 2000 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2014-04-30
• Study Completion Date: 2014-12-31

Brief Summary

Translating reliable evidence on fluid resuscitation of intensive care patients into clinical practice - Improving patient outcomes and containing public health costs

Detailed Description

The Fluid-Translation of Research into Practice Study (TRIPS) is an international, single day, cross-sectional study planned for the second quarter of 2014, coordinated by the George Institute for Global Health, with the purpose of documenting prescribing practices for fluid resuscitation in intensive care units (ICUs) worldwide. This international cross-sectional study follows on from the publication of large-scale randomized controlled trials and meta-analyses of fluid resuscitation, which provide evidence of how fluid resuscitation may affect patient-centered outcomes.

Fluid-TRIPS is a repeat of the Saline versus Albumin for Fluid Evaluation (SAFE)-TRIPS which was an international cross-sectional survey conducted in 2007 that had 391 ICU's participate from 25 countries and provided insight into international fluid resuscitation practice at that time. Along with establishing if fluid resuscitation practices have changed since SAFE-TRIPS, Fluid-TRIPS also aims to determine the relationship between fluid choice and evidence, along with understand other factors that may influence the choice of bolus fluid in clinical practice.

Conditions

Critical Care, Fluid Resuscitation

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

Adult ICU patient receiving Fluid resus

Adult patients present in the ICU at the start of the study day or admitted during the 24-hour study period will be included in the study sample.

No interventions assigned to this group

Eligibility Criteria

Inclusion Criteria

Adult patients present in the ICU on the study day or admitted during the 24-hour study period will be included in the study sample.

Exclusion Criteria

Children under 16 years are excluded

• Minimum Eligible Age: 16 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

The George Institute for Global Health, Australia

OTHER

Sponsor Role: lead

Responsible Party

Naomi Hammond

Co-principle investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Naomi Hammond

Role: STUDY_CHAIR

The George Institute

Colman Taylor

Role: STUDY_CHAIR

The George Institute

Locations

The The George Institute for global health; Critical Care & Trauma Division

Sydney, New South Wales, Australia

Countries

Australia

References

Hammond NE, Taylor C, Finfer S, Machado FR, An Y, Billot L, Bloos F, Bozza F, Cavalcanti AB, Correa M, Du B, Hjortrup PB, Li Y, McIntryre L, Saxena M, Schortgen F, Watts NR, Myburgh J; Fluid-TRIPS and Fluidos Investigators; George Institute for Global Health, The ANZICS Clinical Trials Group, BRICNet, and the REVA research Network. Patterns of intravenous fluid resuscitation use in adult intensive care patients between 2007 and 2014: An international cross-sectional study. PLoS One. 2017 May 12;12(5):e0176292. doi: 10.1371/journal.pone.0176292. eCollection 2017.

Reference Type: DERIVED

PMID: 28498856 (View on PubMed)

Other Identifiers

ACTRN12613001172796

Identifier Type: OTHER

Identifier Source: secondary_id

GI-CCT300413

Identifier Type: -

Identifier Source: org_study_id