Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
606 participants
OBSERVATIONAL
2013-02-28
2013-12-31
Brief Summary
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Detailed Description
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The experimental design is a multi-center, random-order, double-blind observational study to investigate the salty taste and salt intake in population-level.
A total of 606 individuals from four cities in China are recruited in this study. This study aims to explore the salty taste characterization and salt intake in participants who like or dislike spicy diet through questionnaire, spicy preference, salty perception and super-threshold as well as the 24-hour urinary sodium excretion.
Conditions
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Study Design
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ECOLOGIC_OR_COMMUNITY
CROSS_SECTIONAL
Study Groups
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Different degree of spicy food intake
No Intervention
Interventions
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No Intervention
Eligibility Criteria
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Inclusion Criteria
* Willing and able to provide written informed consent.
* Willing and able to comply with all study procedures.
Exclusion Criteria
* Capsaicin allergy and poor compliance.
* Recently oral diuretics and participate in other pharmacological experiment in 3 months.
* Acute infection, cancer, serious arrhythmias, drug or alcohol abuse.
* Currently have cold, fever, acidosis, dehydration, diarrhea, vomiting during the study.
* Unwilling or unable to communication due to the dysnoesia and language disorders
* Severe neural or psychiatric diseases that would preclude fully understand and corporation in the study.
* Pregnancy or lactation
* Unwilling to sign the informed consent
18 Years
55 Years
ALL
Yes
Sponsors
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Zhiming Zhu
OTHER
Responsible Party
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Zhiming Zhu
Director of the Dept. of Hypertension & Endocrinology
Locations
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Daping Hospital, The Third Military Medical University
Chongqing, Chongqing Municipality, China
Countries
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References
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Yang D, Luo Z, Ma S, Wong WT, Ma L, Zhong J, He H, Zhao Z, Cao T, Yan Z, Liu D, Arendshorst WJ, Huang Y, Tepel M, Zhu Z. Activation of TRPV1 by dietary capsaicin improves endothelium-dependent vasorelaxation and prevents hypertension. Cell Metab. 2010 Aug 4;12(2):130-41. doi: 10.1016/j.cmet.2010.05.015.
Zhang LL, Yan Liu D, Ma LQ, Luo ZD, Cao TB, Zhong J, Yan ZC, Wang LJ, Zhao ZG, Zhu SJ, Schrader M, Thilo F, Zhu ZM, Tepel M. Activation of transient receptor potential vanilloid type-1 channel prevents adipogenesis and obesity. Circ Res. 2007 Apr 13;100(7):1063-70. doi: 10.1161/01.RES.0000262653.84850.8b. Epub 2007 Mar 8.
Hao X, Chen J, Luo Z, He H, Yu H, Ma L, Ma S, Zhu T, Liu D, Zhu Z. TRPV1 activation prevents high-salt diet-induced nocturnal hypertension in mice. Pflugers Arch. 2011 Mar;461(3):345-53. doi: 10.1007/s00424-011-0921-x. Epub 2011 Jan 19.
Other Identifiers
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2012CB517805
Identifier Type: OTHER_GRANT
Identifier Source: secondary_id
SATIETY-1
Identifier Type: -
Identifier Source: org_study_id
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