Efficacy/Safety Study to Explore a New Revised Topical Formulation in Atopic Dermatitis

NCT ID: NCT01948869

Last Updated: 2014-08-07

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

35 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-10-31

Study Completion Date

2014-06-30

Brief Summary

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The study shall explore whether treatment of atopic dermatitis is equally effective with respect to a marketed medical device and a new medical device.

Detailed Description

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Conditions

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Dermatitis, Atopic

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

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Phoenix II

Application over 29 days twice daily

Group Type EXPERIMENTAL

Phoenix II (BAY81-2996)

Intervention Type DEVICE

Phoenix I

Application over 29 days twice daily

Group Type ACTIVE_COMPARATOR

Phoenix I (BAY81-2996)

Intervention Type DEVICE

Untreated skin

Untreated skin areas of subjects will be observed over 29 days

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Phoenix II (BAY81-2996)

Intervention Type DEVICE

Phoenix I (BAY81-2996)

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Male or female Caucasians aged between 18 and 60 years
* Patients with mild to moderate AD (Atopic Dermatitis) presenting a scoring AD (SCORAD) rating below 50
* Skin type I - IV according to Fitzpatrick
* Acute AD symptoms on each assessment areas (local SCORAD ≥ 3 and \</= 12) at Baseline
* Acute symptom of pruritus at Baseline

Exclusion Criteria

* Any other skin disease at the test area that would interfere the clinical assessment in the opinion of the investigator
* Moles, tattoos, strong pigmentation, or scars at the test area that would interfere the clinical assessment
* Regular intake of antiphlogistic drugs (for example, nonsteroidal anti-inflammatory drug \[NSAIDs\])
* Any condition or treatment which might influence the trial (e.g. any treatment with topical antibiotics, antifungals, or corticoids) within 14 days prior to screening as well as during the trial (exception: topical treatment of AD lesions other than the test areas (for example, face) with low potency steroids restricted to small areas)
* UV-therapy or the use of solarium within 30 days before screening as well as during the trial
* Any alternative treatment of AD (e.g. acupuncture, kinesiology, and homoeopathy) within 30 days before screening as well as during the trial
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Bayer

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bayer Study Director

Role: STUDY_DIRECTOR

Bayer

Locations

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Münster, North Rhine-Westphalia, Germany

Site Status

Countries

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Germany

Other Identifiers

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2013-002569-20

Identifier Type: EUDRACT_NUMBER

Identifier Source: secondary_id

16960

Identifier Type: -

Identifier Source: org_study_id

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