Efficacy/Safety Study to Explore a New Topical Formulation in Atopic Dermatitis

NCT ID: NCT01691209

Last Updated: 2013-08-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2013-10-31

Study Completion Date

2014-06-30

Brief Summary

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The study shall explore whether treatment of atopic dermatitis is equally effective with Phoenix medical device as compared to standard therapy (Hydrocortisone cream).

Detailed Description

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Conditions

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Dermatitis, Atopic

Keywords

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Phoenix Hydrocortison mild atopic dermatitis efficacy safety

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Investigators

Study Groups

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Phoenix

Application over 29 days twice daily

Group Type EXPERIMENTAL

Phoenix (BAY81-2996)

Intervention Type DEVICE

Topical formulation applied to the skin

Hydrocortison

Application over 29 days twice daily

Group Type ACTIVE_COMPARATOR

1% Hydrocortison cream

Intervention Type DRUG

1% Hydrocortison cream applied to the skin

Untreated skin

Participants will be observed over 29 days without study treatment

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Phoenix (BAY81-2996)

Topical formulation applied to the skin

Intervention Type DEVICE

1% Hydrocortison cream

1% Hydrocortison cream applied to the skin

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Male or female Caucasians aged between 18 and 60 years
* Patients with mild atopic dermatitis (AD) presenting a scoring AD (SCORAD) rating below 50
* Skin type I - IV according to Fitzpatrick
* Acute AD symptoms on each assessment areas (local SCORAD ≥ 3 and \<= 12) at Baseline
* Acute symptom of pruritus at Baseline

Exclusion Criteria

* Any other skin disease at the test area that would interfere with the clinical assessment in the opinion of the investigator
* Moles, tattoos, strong pigmentation, or scars at the test area that would interfere with the clinical assessment
* Regular intake of antiphlogistic drugs (for example nonsteroidal anti-inflammatory drugs \[NSAIDs\])
* Any condition or treatment which might influence the trial (e.g. any treatment with topical antibiotics, antifungals, or corticoids) within 14 days prior to screening as well as during the trial (exception: topical treatment of AD lesions other than the test areas (for example, face) with low potency steroids restricted to small areas)
* UV-therapy or the use of solarium within 30 days before screening as well as during the trial
* Any alternative treatment of AD (e.g. acupuncture, kinesiology, and homoeopathy) within 30 days before screening as well as during the trial
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Bayer

INDUSTRY

Sponsor Role lead

Responsible Party

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Bayer HealthCare AG, Consumer Care

Principal Investigators

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Bayer Study Director

Role: STUDY_DIRECTOR

Bayer

Locations

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Münster, North Rhine-Westphalia, Germany

Site Status

Countries

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Germany

Other Identifiers

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2012-001504-38

Identifier Type: EUDRACT_NUMBER

Identifier Source: secondary_id

16200

Identifier Type: -

Identifier Source: org_study_id