The Comparison of Effect of Four Different Treatment Protocols on IVF Outcomes in Poor Responders Undergoing in Vitro Fertilization.

NCT ID: NCT01948804

Last Updated: 2014-01-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE4

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-01-31

Brief Summary

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The comparison of effect of four different treatment protocols: Antagonist/letrozole protocol, microdose flare-up protocol, Antagonist/clomiphene protocol, Antagonist on IVF outcomes in poor responders undergoing in vitro fertilization; a prospective randomized-controlled study.

Detailed Description

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Conditions

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Poor Responders Undergoing IVF

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Caregivers

Study Groups

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IVF patients

patients that has applied to Yeditepe University Hospital assisted reproduction center

Group Type EXPERIMENTAL

GnrH Antagonist/letrozole protocol (Cetrotide; serono + Femara; Novartis Pharma AG)

Intervention Type DRUG

microdose flare-up protocol (Lucrin; Abbott + Gonal F, Serono)

Intervention Type DRUG

Antagonist/clomiphene protocol (Cetrotide; serono + Klomen, Kocak pharma)

Intervention Type DRUG

GnRH antagonist protocol (Cetrotide, Serono)

Intervention Type DRUG

Interventions

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GnrH Antagonist/letrozole protocol (Cetrotide; serono + Femara; Novartis Pharma AG)

Intervention Type DRUG

microdose flare-up protocol (Lucrin; Abbott + Gonal F, Serono)

Intervention Type DRUG

Antagonist/clomiphene protocol (Cetrotide; serono + Klomen, Kocak pharma)

Intervention Type DRUG

GnRH antagonist protocol (Cetrotide, Serono)

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

Criteria for definition of poor responders included at least one of the following

1. Anti müllerian hormone \<1.1 ng/ml and/or a previous poor ovarian response (≤3 oocytes with a conventional stimulation protocol).
2. Primary infertile patients
3. BMI≤30 kg/m2 were included this study.

Exclusion Criteria

\-
Minimum Eligible Age

18 Years

Maximum Eligible Age

44 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Pınar Özcan Cenksoy

OTHER

Sponsor Role lead

Responsible Party

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Pınar Özcan Cenksoy

Medical Doctor

Responsibility Role SPONSOR_INVESTIGATOR

Other Identifiers

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ytu-123

Identifier Type: OTHER

Identifier Source: secondary_id

ytu-123

Identifier Type: -

Identifier Source: org_study_id

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