The Effects of β-Hydroxy-β-methylbutyrate Free Acid and High-Intensity Interval Training
NCT ID: NCT01941368
Last Updated: 2014-03-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
40 participants
INTERVENTIONAL
2013-09-30
2013-12-31
Brief Summary
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Subjects: Fifty males and females between the ages of 18 - 35 will be recruited to participate in this study. Subject will be randomized to one of three groups: a control group (CTL), an HIIT only group (HIIT) or a group which will take the amino acid metabolite HMB and perform HIIT (HMB-HIIT). Individuals assigned to CTL will undergo baseline testing. They will then be asked to continue their normal exercise routine for 4 weeks and will undergo post-testing after this time period.
Study Protocol: Two testing sessions, on nonconsecutive days, will occur at least 72 hours prior to the start of the training period. The same testing protocols will be repeated at the end of the 4-week training period. Testing protocols include performance testing (VO2peak, lactate threshold, critical power, anaerobic working capacity and neuromuscular economy) and anthropometric measures (physiological cross-sectional area and muscle quality). The training protocol for individuals in the experimental groups will consist of 4-weeks of high intensity interval training with three sessions per week on an electronically braked cycle ergometer. Individual work -loads will be calculated based on the outcomes from each participant's preliminary testing.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
BASIC_SCIENCE
TRIPLE
Study Groups
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Control
Individuals assigned to Control Group will undergo baseline testing and then be asked to continue their normal exercise routine for 4 weeks and will undergo post-testing (visits 16 and 17) after this time period.
No interventions assigned to this group
Placebo + High-Intesnity Interval Training (HIIT)
On training days, individuals will consume 1 gram of placebo 30 min prior to training, 1gram placebo 1 hour post training, and 1gram placebo 3 hours post training. On non-training days, individuals will consume placebo 3 times per day (8am, 12pm and 4pm).
Placebo
High Intensity Interval Training
HMB-FA + HIIT
On training days, individuals will consume 1 gram HMB-FA 30 min prior to training, 1gram HMB-FA 1 hour post training, and 1gram HMB-FA 3 hours post training. On non-training days, individuals will consume HMB-FA 3 times per day (8am, 12pm and 4pm).
HMB-FA
High Intensity Interval Training
Interventions
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Placebo
HMB-FA
High Intensity Interval Training
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Free of any physical limitations as determined by the Confidential Medical and Activity questionnaire and/or PAR-Q
* Between the ages of 18 and 35
Exclusion Criteria
* Any chronic illness that causes continuous medical care
18 Years
35 Years
ALL
Yes
Sponsors
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Metabolic Technologies Inc.
INDUSTRY
Responsible Party
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Principal Investigators
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Jeffery Stout, PhD
Role: PRINCIPAL_INVESTIGATOR
University of Central Florida
Locations
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University of Central Florida, Sport and Exercise Science
Orlando, Florida, United States
Countries
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References
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Robinson EH 4th, Stout JR, Miramonti AA, Fukuda DH, Wang R, Townsend JR, Mangine GT, Fragala MS, Hoffman JR. High-intensity interval training and beta-hydroxy-beta-methylbutyric free acid improves aerobic power and metabolic thresholds. J Int Soc Sports Nutr. 2014 Apr 26;11:16. doi: 10.1186/1550-2783-11-16. eCollection 2014.
Other Identifiers
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13-257
Identifier Type: OTHER
Identifier Source: secondary_id
MTI2013-CS03
Identifier Type: -
Identifier Source: org_study_id
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