Metabolomics of Liver Regeneration Following Partial Hepatectomy in Healthy Living Liver Donors

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-08-31

Study Completion Date

2016-09-26

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The PI will study metabolism during liver regeneration in living liver donors

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Changes in Body Composition and Nutritional Status in Patients Undergoing Liver Transplantation

NCT02023190

Liver Cirrhosis

UNKNOWN

Evaluation of Patients With Liver Disease

NCT00001971

Hepatitis D Hepatitis C Hepatitis B +1 more

RECRUITING

Longitudinal Outcomes in Hepatic Resection

NCT02997098

Liver Diseases Surgery

WITHDRAWN

Prospective, Observational Study of Biomarkers in Liver Cancer - Identification of Actionable Events

NCT01963949

Hepatocellular Carcinoma

WITHDRAWN

Liver Regeneration After Liver Resection

NCT01220986

Liver Diseases Hepatectomy

UNKNOWN

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Samples of blood and urine will be collected from study participants at defined timepoints. The samples will be evaluated to study the metabolism of the regenerating liver after a portion of the liver has been donated from a living donor.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Liver Insufficiency

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

1. Potential donor must be in excellent medical and psychological health.
2. Potential donor must be between the ages of 18 and 60.
3. Must have a compatible blood type to the recipient.
4. Must have health care coverage for non-donor related health issues that arise post donation
5. Recipient and donor must have compatible body size.
6. Donors Body Mass Index (BMI) must be less than 30.
7. All previous donor abdominal surgeries will be reviewed on a case by case basis by the surgeon.

Exclusion Criteria

1. Positive blood test for Human Immunodeficiency Virus, Hepatitis C virus, Hepatitis B virus
2. The size of the donor liver is not large enough to safely resection and still retain enough volume to function normally after the surgery.
3. Liver biopsy show liver cirrhosis or early stages of HCC.

\-

\-

Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes