Assessment of Renal Function in Cirrhotic Patients

NCT ID: NCT01895114

Last Updated: 2025-10-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

213 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-12-31

Study Completion Date

2025-01-13

Brief Summary

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The purpose of this study is to help determine whether cystatin C is a more sensitive laboratory measurement for renal function in cirrhotic patients.

Detailed Description

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Serum cystatin C, creatinine clearance based calculations, and 125I-Iothalamate clearance (Glofil) will be obtained in 220 patients with cirrhosis. Utilizing this information, the correlation between cystatin C and 125I-Iothalamate clearance will be obtained. In addition, the current serum creatinine based calculations and true creatinine clearance will also be correlated with 125I-Iothalamate clearance. The results of this study should help to determine whether serum cystatin C is a more sensitive laboratory measurement of renal function in patients with cirrhosis.

Conditions

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Liver Failure Renal Failure

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* over 18 undergoing evaluation for a liver transplant

Exclusion Criteria

* known allergy or sensitivity to 125I-Iothalamate
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Baylor Research Institute

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Bernard Fischbach, MD

Role: PRINCIPAL_INVESTIGATOR

Baylor All Saints

Locations

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Baylor All Saint's Medical Center in Fort Worth

Fort Worth, Texas, United States

Site Status

Countries

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United States

Other Identifiers

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010-263

Identifier Type: -

Identifier Source: org_study_id

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