Utility of Renal Biomarkers in Cirrhosis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

105 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-10-31

Study Completion Date

2012-10-31

Brief Summary

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Evaluation of kidney function is critical in cirrhotic patients as there is a clear relationship between renal failure and prognosis. The investigators hypothesized that in this population new biomarkers of renal function could help in early detection of acute renal failure and in discrimination between renal and pre-renal causes. Finally the investigators hypothesized that such biomarkers could predict short-term outcome in this population.

Detailed Description

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Conditions

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Cirrhosis Ascitis

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Age ≥ 18 years
* Known or suspected cirrhosis
* Suspected ascitis
* Informed consent signed

Exclusion Criteria

* Proven multifocal hepatocellular carcinoma
* Acute gastric hemorrhage (active or \< 2 weeks)
* Known end-stage renal disease or on dialysis before admission
* Recipients of kidney or liver transplants
* Transferred from another institution

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Ponte Belen

Dr

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Belen Ponte, Md

Role: PRINCIPAL_INVESTIGATOR

Nephrology Division

Locations

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University Hospital of Geneva

Geneva, , Switzerland

Site Status

Countries

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Switzerland

Other Identifiers

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PRD 2010-I-15

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

10-056 Med 10-019

Identifier Type: -

Identifier Source: org_study_id