Music & Cancer - Live Music During Chemotherapy

NCT ID: NCT01870479

Last Updated: 2018-06-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

143 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-05-31

Study Completion Date

2017-03-31

Brief Summary

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Main purpose: To determine if live music moderates the level of chemotherapy related anxiety, in patients with haematological cancer

The investigators hypothesize that live music:

1. Have an ameliorating effect on physical and psychological symptoms during chemotherapy treatment
2. May counteract the patients feeling of loss of identity and alienation in this particular group of cancer patients.
3. Is more effective in patients with good musical abilities.
4. Is more effective than taped music.

Method: Intervention groups:

1. Listening to patient-preferred live music during chemotherapy
2. Listening to patient-preferred taped music during chemotherapy
3. Standard care

Endpoints:

Primary: Level of anxiety measured by STAI. Secondary: Serum catecholamines.

Background: In order to establish the intervention procedures, the investigators have carried out a pilot study at the hematology department at Hospital of Southwest Denmark, including students from the Academy of Music and Dramatic Arts, Southern Denmark. The pilot results indicates that live music has an uplifting, pain relieving, and then releasing effect and that music has a positive impact on hospitalisation. According to the evaluation forms filled out by 243 cancer patients, the music experience has provided human anchorage/cohesion as a counterweight to disease fixation and alienation Chemotherapy involves major physical and psychological problems. Not much has been provided in the clinical setting which relieves the symptoms of anxiety associated with chemotherapy. A review of the literature illustrate the need for developing new potential areas of intervention that takes into account, that not only do cancer patients face challenges in everyday life ranging from physiological changes over social to psychological problems, but also during treatment procedures, which may cause a higher level of anxiety associated with these procedures, e.g., chemotherapy infusion.This project investigates to what degree live music may relieve some of these symptoms during treatment for haematological cancer. The project is created in order to both measure psychosocial effects as well as direct stress measures, i.e. serum catecholamine. These physiological changes are measured in order to shed light on the mechanism behind the potential effects of live music on discomfort in connection with chemotherapy treatment.

Perspectives: The vision of the project focus on strengthening the cancer patients' ability to cope with physiological and psychological issues during chemotherapy sessions and to make the patients conscious of music as an option in these coping efforts. Hopefully, the results will provide a scientific basis for an evaluation of the perspectives and the potentials of live music treatment during chemotherapy infusion among cancer patients.

Detailed Description

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Conditions

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Non Hodgkin´s Lymphomas Hodgkin´s Lymphomas

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Live music

Patient preferred live music during chemotherapy session.

Group Type EXPERIMENTAL

Live music

Intervention Type OTHER

Taped music

Patient preferred taped music during chemotherapy

Group Type ACTIVE_COMPARATOR

Taped music

Intervention Type OTHER

Control

Usual care during chemotherapy

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Live music

Intervention Type OTHER

Taped music

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age 18+
* Newly diagnosed with malignant lymphoma and planned first line chemotherapy treatment
* Able to give informed consent

Exclusion Criteria

* Patients who do not speak or understand Danish
* Patients who are deaf or blind.
* Any comorbidity that postpone planed chemotherapy for more than 4 weeks
* Patients with alcohol or drugs misuse problems as stated in the medical record.
* Patients with untreated mental illness as identified in the medical record
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Danish Cancer Society

OTHER

Sponsor Role collaborator

University of Aarhus

OTHER

Sponsor Role collaborator

Margrethe Langer Bro

OTHER

Sponsor Role lead

Responsible Party

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Margrethe Langer Bro

Assistant professor

Responsibility Role SPONSOR_INVESTIGATOR

Principal Investigators

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Margrethe L Bro, PhD student

Role: PRINCIPAL_INVESTIGATOR

IRS, Southern Denmark. Assistant professor at The Academy of Music in Southern Denmark

Locations

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Aarhus University Hospital

Aarhus, Central Jutland, Denmark

Site Status

Hospital of Southwest Jutland

Esbjerg, Region of Southwest Denmark, Denmark

Site Status

Odense University Hospital

Odense, Region of Southwest Denmark, Denmark

Site Status

The Academy of Music and Dramatic Arts, Southern Denmark

Odense, Region of Southwest Denmark, Denmark

Site Status

Roskilde Sygehus

Roskilde, Region Sjælland, Denmark

Site Status

Rigshospitalet

Copenhagen, The Capital Region of Denmark, Denmark

Site Status

Herlev Hospital

Copenhagen, The Capital Region of Denmark, Denmark

Site Status

Countries

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Denmark

Other Identifiers

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S-20120118

Identifier Type: -

Identifier Source: org_study_id

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