Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
273 participants
OBSERVATIONAL
2010-10-31
2015-11-30
Brief Summary
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After a traumatic spinal cord injury, a severe bone loss in the paralyzed extremities is observed. This leads to a osteoporosis which is connected to a high fracture risk.
Aims:
To compare the two measurement methods DEXA and pQCT concerning optimal diagnostics and assessment of fracture risk in subjects with spinal cord injury.
Subjects:
250 women and 250 men (ageā„18, any AIS-classification) with an acute or chronic spinal cord injury will be recruited for this study. For a reference group, 500 able-bodied persons will be measured analogously.
Methods:
Using DEXA-Osteodensitometry, bone parameters of the lumbar vertebral column, proximal femur, distal radius, distal tibia and knee area will be assessed. Additionally, geometric bone parameters of the tibia will be measured by using pQCT. All measurements will be done unilaterally. For the assessment of potential risk factors for reduced bone stiffness after spinal cord injury a questionnaire will be used.
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Detailed Description
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Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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Spinal Cord Injury
Persons with spinal cord injury Osteodensitometry DXA pQCT
DXA
Osteodensitometry
pQCT
Osteodensitometry
Reference
Reference population (able-bodied) Osteodensitometry DXA pQCT
DXA
Osteodensitometry
pQCT
Osteodensitometry
Interventions
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DXA
Osteodensitometry
pQCT
Osteodensitometry
Eligibility Criteria
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Inclusion Criteria
* mobilized patients
* written informed consent
Exclusion Criteria
* limited mobility
* contractures of the lower limbs
* decubitus ulcer
* pregnancy
18 Years
ALL
Yes
Sponsors
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Swiss Paraplegic Research, Nottwil
NETWORK
Responsible Party
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Principal Investigators
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Angela Frotzler, PhD
Role: PRINCIPAL_INVESTIGATOR
Swiss Paraplegic Research, Nottwil
Locations
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Swiss Paraplegic-Centre
Nottwil, Canton of Lucerne, Switzerland
Countries
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Related Links
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Swiss Paraplegic Centre Nottwil
Other Identifiers
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2010-13
Identifier Type: -
Identifier Source: org_study_id
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