Quartet™ Bad Oeynhausen Trial

NCT ID: NCT01850264

Last Updated: 2019-01-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

81 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-03-31

Study Completion Date

2018-12-31

Brief Summary

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Primary objective of this study is to evaluate whether the use of a quadripolar left ventricular (LV) electrode compared to a standard bipolar LV electrode leads to lower non-responder rates in patients undergoing cardiac resynchronization therapy (CRT)

Detailed Description

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Conditions

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Congestive Heart Failure Cardiac Resynchronization Therapy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Quadripolar LV electrode

Application of a quadripolar LV electrode

Group Type ACTIVE_COMPARATOR

Application of quadripolar / bipolar LV electrodes

Intervention Type DEVICE

Bipolar LV electrode

Application of a bipolar LV electrode

Group Type ACTIVE_COMPARATOR

Application of quadripolar / bipolar LV electrodes

Intervention Type DEVICE

Interventions

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Application of quadripolar / bipolar LV electrodes

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Indication for CRT-D implantation according to current guidelines
* Ischemic cardiomyopathy (ICM) or dilated cardiomyopathy (DCM)
* Sinus rhythm
* NYHA II-IV
* Age ≥ 18 years
* Written informed consent to participate in the study

Exclusion Criteria

* Right bundle brunch block
* Valvular cardiomyopathy
* Patient receiving a non-transvenous LV electrode
* Known pregnancy
* Age \< 18 years
* Life expectancy \< 1 year
* Atrial fibrillation / atrial flutter at the time of enrolment
* Inability to provide informed consent
* Participation in another study with active therapeutic arm
* Regular follow-up in the study center within the first 6 months after implantation not guaranteed
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Heart and Diabetes Center North-Rhine Westfalia

OTHER

Sponsor Role lead

Responsible Party

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Klaus Juergen Gutleben

Senior cardiologist

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Klaus-Juergen Gutleben, M.D.

Role: PRINCIPAL_INVESTIGATOR

Heart and Diabetes Center North Rhine-Westphalia, Department of Cardiology

Locations

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Department of Cardiology, Heart and Diabetes Center North Rhine-Westphalia, Ruhr University Bochum

Bad Oeynhausen, , Germany

Site Status

Countries

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Germany

Other Identifiers

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HDZNRW_KA_002_KJG

Identifier Type: -

Identifier Source: org_study_id

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