Non-invasive Measuring of Cerebral Perfusion After Severe Brain Injury With Near-infrared-spectroscopy and ICG
NCT ID: NCT01836848
Last Updated: 2013-04-22
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
30 participants
INTERVENTIONAL
2013-06-30
2016-06-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
DIAGNOSTIC
NONE
Study Groups
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indocyanine green
in this arm we do the Intervention 'measuring cerebral perfusion by NIRS with ICG', the pat. gets before a CT-Scan with perfusion measurement a indocyanine green bolus i.v. and a measurement of cerebral perfusion with near-infrared-spectroscopy
measuring cerebral perfusion by NIRS with ICG
application of a bolus of 5mg indocyanine green (ICG) in 3ml saline 0,9% i.v. in 1 second and measuring the ICG turnover with the near-infrared-spectroscopy (NIRS)
Interventions
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measuring cerebral perfusion by NIRS with ICG
application of a bolus of 5mg indocyanine green (ICG) in 3ml saline 0,9% i.v. in 1 second and measuring the ICG turnover with the near-infrared-spectroscopy (NIRS)
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* onset of clinical symptoms of subarachnoid or intracranial haemorrhage or trauma suffered less than 72h
* indication for implanting a tissue oxygen and intracranial pressure probe
* A signed informed consent by the patient or legal guardian
Exclusion Criteria
* Open injuries in the area of the planned optodes
* Malignant primary disease under chemotherapy
* pregnancy
* bleeding disorder
* In the short term unfavorable prognosis (eg, bilateral wide and light-fixed pupils)
* Patients with pacemakers or where no MRI compatibility is due to non- removable metal parts
* contraindications for contrast media in CT (eg, iodine allergy)
* Untreated hyperthyroidism
* End Stage Renal Disease
* severe psychomotor agitation
18 Years
80 Years
ALL
No
Sponsors
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University of Cologne
OTHER
Responsible Party
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Gerrit Brinker
senior physician
Principal Investigators
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Gerrit Brinker, physician
Role: PRINCIPAL_INVESTIGATOR
Universitiy of Cologne, Departement of General Neurosurgery
Locations
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Departement of General Neurosurgery of th University of Cologne
Cologne, , Germany
Countries
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Facility Contacts
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Other Identifiers
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NCH-NIRS-001
Identifier Type: -
Identifier Source: org_study_id
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