Multimodal Monitoring Study in Neuro Critical Care

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-01-01

Study Completion Date

2030-12-01

Brief Summary

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During the first week after an acute cerebral injury, neurologic clinical exam is often irrelevant, limited by sedation use or spontaneous consciousness disorders.

Hence, neurological monitoring of brain oxygen consumption, metabolic disorders, electrical activity is used to follow and prevent delayed cerebral injuries. Among those instruments, numerous are often described: intra cranial pressure monitoring, brain tissue oxygen pressure monitoring, scalp electroencephalography, continuous electroencephalography and Near infrared Red Spectroscopy (NIRS).

Even if the value of some of those technologies are well known, many remain part of a research domain. Here we will not only try to study the correlation between different cerebral autoregulation's index described in the scientific literature but also will we try to identify and describe EEG and cardiorespiratory changes during the first week following brain injury. The objective of this study is to investigate the pathophysiology of acute brain injury and explore potent biomarkers of multimodal monitoring during the first week following acute brain injury.

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Detailed Description

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Conditions

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Subarachnoidal Hemorrhage Intacranial Hypertension Acute Trauma Brain Injury

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Patients admitted in neurocritical care in Pierre Wertheimer hospital, following acute brain injury,

Study the evolution and correlation between cerebral autoregulation index

Intervention Type OTHER

Objective n°1: Study the correlation between autoregulation index:

The investigators will look for a correlation between several auroregulation index such as the PRx, ORx and Cox.

Objective n°2: Evaluation and detection of EEG prognostic patterns: The investigators will look for quantitaive EEG changes during the early phase of acute brain injuries.

Interventions

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Study the evolution and correlation between cerebral autoregulation index

Objective n°1: Study the correlation between autoregulation index:

The investigators will look for a correlation between several auroregulation index such as the PRx, ORx and Cox.

Objective n°2: Evaluation and detection of EEG prognostic patterns: The investigators will look for quantitaive EEG changes during the early phase of acute brain injuries.

Intervention Type OTHER