Limb Remote Ischemic Preconditioning for Heart and Intestinal Protection During Laparoscopic Colorectal Surgery

NCT ID: NCT01832337

Last Updated: 2013-04-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-10-31

Brief Summary

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Remote ischaemic preconditioning may confer the cytoprotection in critical organs. The investigators hypothesized that limb remote ischemic preconditioning (RIPC) would reduce heart and gastrointestinal function injury in middle-aged and elderly patients undergoing elective laparoscopic colorectal surgery.

Detailed Description

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Conditions

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Laparoscopic Colorectal Surgery

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Participants

Study Groups

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precondition

Group Type EXPERIMENTAL

Limb remote ischemic preconditioning (LRIP)

Intervention Type PROCEDURE

Limb remote ischemic preconditioning (LRIP) consisted of three cycles of left upper limb ischemia induced by inflating a blood pressure cuff on the left upper arm to 200mmHg, with an intervening 5 minutes of reperfusion, during which time the cuff was deflated.

Interventions

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Limb remote ischemic preconditioning (LRIP)

Limb remote ischemic preconditioning (LRIP) consisted of three cycles of left upper limb ischemia induced by inflating a blood pressure cuff on the left upper arm to 200mmHg, with an intervening 5 minutes of reperfusion, during which time the cuff was deflated.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* age \>40 years old
* ASA I-II
* receive elective laparoscopic colorectal surgery
* written informed consent can be obtained

Exclusion Criteria

* coagulation disorders
* patients with cardiac pacemaker
* patients with severe cardiac,or pulmonary,hepatic,renal disease ,or can not tolerate laparoscopic surgery
* patients with peripheral vascular disease affecting the upper limbs
* patients with mental,or hearing, vision disorder, who is not able to communicate with physicians
* difficult airways that can not receive rapid induction
Minimum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Fei Li

OTHER

Sponsor Role lead

Responsible Party

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Fei Li

Sixth Affiliated Hospital, Sun Yat-sen University

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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the Sixth Affiliated Hospital, Sun Yat-sen University

Guangzhou, Guangdong, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Fei Li

Role: CONTACT

86-13580374947

Facility Contacts

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Fei Li

Role: primary

13580374947

Other Identifiers

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伦研批第E201215号

Identifier Type: -

Identifier Source: org_study_id

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