An Integrated Treatment for Comorbid PTSD and Substance Abuse in Adolescents

NCT ID: NCT01825694

Last Updated: 2023-09-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

117 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-04-30

Study Completion Date

2015-05-31

Brief Summary

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This study plans to develop an integrated treatment for comorbid post-traumatic stress disorder (PTSD) and substance abuse (SA) in adolescents. The investigators aim to develop a treatment approach that is community-friendly, well-tolerated, and deliverable by substance abuse counselors (SAC) in outpatient settings. The proposed Trauma-Focused Substance Abuse Treatment (TFSAT) aims to reduce PTSD symptoms and substance use and build coping skills. The investigators propose to adapt an evidence-based trauma program, Cognitive-Behavioral Intervention for Trauma in Schools (CBITS), for adolescent substance abusers (ASAbusers); to assess the acceptability and feasibility of the integrated approach; and to pilot test the new program against standard care.

The investigators hypothesize that the intervention group, compared to the control group, will reduce substance use and symptoms for traumatic stress.

Detailed Description

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Conditions

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Substance Abuse Traumatic Stress

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Standard of Care

The Standard of Care condition includes: 1) an individual session with the counselor, once per week; 2) a treatment group with the counselor, twice per week; and 3) parents of youth are invited to attend parent-only educational sessions weekly.

Group Type NO_INTERVENTION

No interventions assigned to this group

Trauma-focused Substance Abuse Intervention

See Intervention Arm description.

Group Type EXPERIMENTAL

Trauma-focused Substance Abuse Intervention

Intervention Type BEHAVIORAL

An integrated treatment approach to reduce substance use and PTSD symptoms. The intervention program includes: 1) 1-2 individual sessions during which youth talk about the trauma, during the course of the intervention program; 2) 16 group sessions for youth; 3) 2 conjoint sessions with parents to improve communication and problem-solving skills; and 4) 2 parent-education group sessions.

Interventions

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Trauma-focused Substance Abuse Intervention

An integrated treatment approach to reduce substance use and PTSD symptoms. The intervention program includes: 1) 1-2 individual sessions during which youth talk about the trauma, during the course of the intervention program; 2) 16 group sessions for youth; 3) 2 conjoint sessions with parents to improve communication and problem-solving skills; and 4) 2 parent-education group sessions.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Between ages of 13 \& 19;
* meeting DSM IV criteria for substance abuse/dependence and PTSD;
* previously enrolled at recruitment site for at least 2 weeks;
* parent/guardian provides permission for minors to participate.


* Age 18 or above;

Exclusion Criteria

* Not within the specified age range;
* presence of organic brain damage;
* inability to understand enrollment forms (e.g. Informed Assent/Consent Form)


* presence of organic brain damage.
Minimum Eligible Age

13 Years

Maximum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of California, Los Angeles

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Nancy S Wu, MD

Role: PRINCIPAL_INVESTIGATOR

University of California, Los Angeles

Locations

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Behavioral Health Services

Los Angeles, California, United States

Site Status

Countries

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United States

Other Identifiers

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1R34DA031301

Identifier Type: NIH

Identifier Source: org_study_id

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