Organ Donor Tissue Oxygen Saturation as a Predictor of Number of Organs to Transplant Per Donor
NCT ID: NCT01819116
Last Updated: 2016-01-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
60 participants
OBSERVATIONAL
2013-04-30
2014-03-31
Brief Summary
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Detailed Description
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1. Evaluate the association between StO2 level in the DNC organ donor and the number of organs transplanted per donor;
2. Evaluate whether or not tissue perfusion in the DNC organ donor population correlates with currently measured macro-hemodynamic variables during the donor management phase.
3. Assess if StO2 in the DNC organ donor is related to the number of organs with normal end-organ function, and with the number of organs predicted to be transplanted using the organ donor calculator.
4. Assess if StO2 in the DNC organ donor is related with intravenous thyroid hormone treatment.
Investigators will conduct an observational study, including 60 DNC organ donors, in Lifebanc's Donor Service Area (DSA). Investigators will monitor and record blindly the StO2 with near-infrared spectroscopy (NIRS) in the DNC organ donor from the beginning of the OPO (Organ Procurement Organization) organ donor management period until cardiac arrest in the operating room at the time of recovery.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
2. Age ≥ 15 years old
3. Weight ≥ 45 Kg
Exclusion Criteria
2. Living donor
15 Years
ALL
No
Sponsors
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The Cleveland Clinic
OTHER
Responsible Party
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Silvia Perez-Protto, MD
M.D.
Principal Investigators
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Silvia Perez-Protto, MD
Role: PRINCIPAL_INVESTIGATOR
The Cleveland Clinic
Daniel Lebovitz, MD
Role: STUDY_DIRECTOR
Akron Children Hospital - Lifebanc
J. Steven Hata, MD
Role: STUDY_DIRECTOR
The Cleveland Clinic
Locations
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Cleveland Clinic
Cleveland, Ohio, United States
Countries
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Other Identifiers
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13-020
Identifier Type: -
Identifier Source: org_study_id
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