Effects of Added D-fagomine on Glycaemic Responses to Sucrose

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

View full results

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

14 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-09-30

Study Completion Date

2013-03-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to determine whether D-fagomine affects glycaemic responses to sucrose (commercial white sugar)and quantify the response

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

The Effects of D-Fagomine on Glycaemic Response to Sucrose in Men

NCT01528631

Glycaemic Response Insulinemic Response

COMPLETED NA

Exploring Buckwheat's Glucose Lowering Potential

NCT00841503

Type 2 Diabetes

COMPLETED

Effect of the Extract of the Flour Fermented With Bacillus Subtilis Var Natto DC-15 on Postprandial Glucose

NCT02300181

Prediabetes

COMPLETED NA

Effect of a Food Supplement on Glycemic Parameters in Patients With Impaired Glucose Metabolism

NCT07263802

Impaired Fasting Glucose (IFG) Impaired Glucose Tolerance (Prediabetes)

NOT_YET_RECRUITING NA

Glycaemic and Insulinaemic Responses After Consumption of FOS.

NCT02352857

Glycaemia

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

This is a two treatment randomized double-blind crossover study, with each test product replicated twice.

Randomization: Subjects will be randomized to a Williams Latin square design balanced for treatment order.

Washout: 2 days or more (may return on day 3)

Run-in: High carbohydrate diet guidance (\>150 g/d) 1 day before treatment, recommend same sized dinner the previous night (no food record collection required)

Drop-outs: Subjects who have dropped out before visit 2 will be replaced by another subject randomized in their place (the new subject will complete all treatments)

Subjects will report after an overnight (12 hour) fast for baseline sample collection, and will consume the test product in a fasted state.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Reduction of Post-prandial Glycaemic Response

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

D-fagomine

Measure the changes produced on the postprandial Glycaemic response to 50 g of sucrose containing 40 mg D-fagomine, in 200 ml water

Group Type EXPERIMENTAL

D-fagomine

Intervention Type OTHER

Measure the changes produced on the postprandial Glycaemic response

Control

Sucrose 50 g without d-fagomine, in 200 ml water

Group Type PLACEBO_COMPARATOR

D-fagomine

Intervention Type OTHER

Measure the changes produced on the postprandial Glycaemic response

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

D-fagomine

Measure the changes produced on the postprandial Glycaemic response

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Male or female (not less than 40% Male)
* Aged 18 - 55 years
* Have a body mass index between 18.5 to 29.99 kg/m2
* Healthy, non-diabetic, no gastric bypass surgery
* Have a fasting plasma glucose (finger-stick) \<100 mg/dl (\<5.5 mmol/L)
* Willing and able to provide written informed consent