Nutraceutical on Hyperglycemia

NCT ID: NCT04107922

Last Updated: 2019-10-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

148 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-10-01

Study Completion Date

2019-08-31

Brief Summary

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The aim will be to evaluate if Glicoset® 1000, a nutraceutical containing Ilex Paraguariensis, White Mulberry and Chromium Picolinate, can be effective in improving glycemic status in subject with dysglycemia.

Detailed Description

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The aim will be to evaluate if Glicoset® 1000, a nutraceutical containing Ilex Paraguariensis, White Mulberry and Chromium Picolinate, can be effective in improving glycemic status in subject with dysglycemia.

The investigators will enroll patients with impaired fasting plasma glucose (IFG) or impaired glucose tolerance (IGT), not taking hypoglycemic agents (both pharmaceuticals or nutraceutical agents). Patients will be randomized to take placebo or Glicoset® 1000 for 3 months, in a randomized, double-blind, placebo-controlled design. Glicoset® 1000 and placebo will be self-administered once a day, 1 tablet during the breakfast.

Conditions

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Dysglycemia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

TRIPLE

Participants Caregivers Investigators

Study Groups

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Glicoset

Glicoset is a nutraceutical containing Ilex Paraguariensis, White Mulberry and Chromium Picolinate

Group Type ACTIVE_COMPARATOR

Glicoset

Intervention Type DIETARY_SUPPLEMENT

Patients will take a nutraceutical containing Ilex Paraguariensis, White Mulberry and Chromium Picolinate

Placebo

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type OTHER

Patients will take placebo

Interventions

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Glicoset

Patients will take a nutraceutical containing Ilex Paraguariensis, White Mulberry and Chromium Picolinate

Intervention Type DIETARY_SUPPLEMENT

Placebo

Patients will take placebo

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients with impaired fasting glucose (IFG) or impaired fasting glucose (IGT)
* Patients not taking hypoglycemic agents (both pharmaceuticals or nutraceutical agents)

Exclusion Criteria

* Patients with type 1 or type 2 diabetes mellitus
* Patients with impaired hepatic function
* Patient with impaired renal function
* Patients with gastrointestinal disorders
* Patients with current or previous evidence of ischemic heart disease, heart failure, or stroke
* Patients with weight change of \> 3 Kg during the preceding 3 months
* Patients with hystory of malignancy, and significant neurological or psychiatric disturbances, including alcohol or drug abuse.
* Patients taking (within the previous 3 months) hypoglycemic agents, laxatives, beta-agonists (other than inhalers), cyproheptadine, anti-depressants, antiserotoninergics, phenothiazines, barbiturates, oral corticosteroids, and antipsychotics
* Women who were pregnant or breastfeeding or of childbearing potential and not taking adequate contraceptive precautions.
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Pavia

OTHER

Sponsor Role lead

Responsible Party

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Giuseppe Derosa

MD, PhD, FESC

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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IRCCS Policlinico San Matteo

Pavia, Lombardy, Italy

Site Status

Countries

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Italy

Other Identifiers

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P-20180016364

Identifier Type: -

Identifier Source: org_study_id

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