tDCS Applied to the OFC: Effects on Decision-Making and Impulse Control

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-01-31

Study Completion Date

2014-03-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

In this study the investigators aim to assess whether transcranial direct current stimulation (tDCS; a safe and non-invasive method for modulating the activity of specific brain regions) when applied over the orbitofrontal cortex (OFC) is able to modulate decision-making and impulse control in healthy participants.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Use of tDCS Applied to the Orbitofrontal Cortex to Improve Risky Decision-making in a Clinical Population

NCT06110559

Mood Disorders Depression Suicide

UNKNOWN NA

Transcranial Direct Current Stimulation for Impulsivity and Food-related Impulsivity in Obesity

NCT04218383

Impulsive Behavior

SUSPENDED NA

Modulating Impulsivity in Suicidal Adolescents With Transcranial Direct Current Stimulation (tDCS)

NCT03365102

Impulsive Behavior

COMPLETED NA

Effects of tDCS-enhanced Cognitive Control Training on Depression

NCT03518749

Depression Unipolar

UNKNOWN NA

Effects of Transcranial Direct Current Stimulation (tDCS) in the Management of Suicidal Ideation

NCT06009523

Depression and Suicide

RECRUITING NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

In this single-blind, three-arm and sham-controlled study, we will assess whether transcranial direct current stimulation (tDCS; a safe and non-invasive method for modulating the activity of specific brain regions) when applied over the orbitofrontal cortex (OFC) is able to modulate decision-making and impulse control in healthy volunteers. We hypothesize that tDCS applied to the OFC, in comparison to sham tDCS, will significantly enhance decision-making and impulse control. For this study we will enroll 45 healthy individuals aged 18-60 years. These individuals will be assessed with a battery of computerized tasks as well as clinician-administered and self-reported questionnaires on depression and anxiety. Assessments will be carried out before and after a single 30-minute tDCS session.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Impulsive Behavior Suicidal Impulses

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Participants

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Left OFC Group

Anode applied to the left OFC and cathode applied to the right OFC

Group Type EXPERIMENTAL

Transcranial Direct Current Stimulation

Intervention Type DEVICE

Anode placed over the OFC or the DLPFC and cathode placed over the occipital region

Right OFC Group

Anode applied to the right OFC and cathode applied to the left OFC

Group Type EXPERIMENTAL

Transcranial Direct Current Stimulation

Intervention Type DEVICE

Anode placed over the OFC or the DLPFC and cathode placed over the occipital region

Sham tDCS

Group Type SHAM_COMPARATOR

Transcranial Direct Current Stimulation

Intervention Type DEVICE

Anode placed over the OFC or the DLPFC and cathode placed over the occipital region

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Transcranial Direct Current Stimulation

Anode placed over the OFC or the DLPFC and cathode placed over the occipital region

Intervention Type DEVICE

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

tDCS, Brain Polarization

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Men or women aged 18 to 60 years

Exclusion Criteria

* Presence any psychiatric and/or neurological illness
* Psychoactive substance abuse/dependence in the past 6 months
* Current use of medication(s) that might influence cognition and/or affective status
* Presence of an uncontrolled medical disease (e.g., cardiovascular, renal)
* Pregnancy and/or lactation
* Specific contraindication for tDCS (e.g., metallic head implant).

Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes