Prevalence and Incidence of Central Airway Obstruction in Advanced Lung Cancer

NCT ID: NCT01799395

Last Updated: 2017-09-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

45 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-02-28

Study Completion Date

2015-03-31

Brief Summary

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Lung cancer may cause central airway obstruction through several different mechanisms (invasion by the primary tumor, invasion by metastatic lymph nodes, airway metastasis).

The aim of the present study is to determine the prevalence at the time of diagnosis, the incidence at 1 year from the diagnosis, and the predictors of central airway obstruction associated with advanced lung cancer.

Detailed Description

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Conditions

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Lung Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Lung Cancer

All patients with advanced lung cancer candidate for chemotherapy or chemotherapy + radiation therapy will be enrolled and followed-up for 1 year clinically and radiologically (Chest CT) to verify whether or not central airway obstruction is present at the time of diagnosis or occurs in the year following diagnosis (or in the life span from diagnosis and death in patients who die before 1 year of diagnosis). Furthermore, predictor variables possibly associated with central airway obstruction will be studied.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Advanced lung cancer with indication for chemotherapy or chemotherapy + radiation therapy

Exclusion Criteria

* Age \< 18 year
* Pregnancy
* Refusal to sign informed consent
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Maggiore Bellaria Hospital, Bologna

OTHER

Sponsor Role lead

Responsible Party

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Rocco Trisolini

M.D.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Rocco Trisolini, M.D.

Role: PRINCIPAL_INVESTIGATOR

Maggiore Bellaria Hospital, Bologna, Italy

Locations

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Bentivoglio Hospital

Bentivoglio, Emilia-Romagna, Italy

Site Status

Bellaria Hospital

Bologna, Emilia-Romagna, Italy

Site Status

Maggiore Hospital

Bologna, Emilia-Romagna, Italy

Site Status

Budrio Hospital

Budrio, Emilia-Romagna, Italy

Site Status

SS Salvatore Hospital

San Giovanni in Persiceto, Emilia-Romagna, Italy

Site Status

Countries

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Italy

Other Identifiers

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13002-Trisolini

Identifier Type: -

Identifier Source: org_study_id

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