Molecular Assessment of Lymph Nodes in Patients With Resected (Stage I to IIIA) Non-small Cell Lung Cancer

NCT ID: NCT00213733

Last Updated: 2011-08-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2004-06-30

Study Completion Date

2011-08-31

Brief Summary

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This is a prospective study of surgically resected samples and lymph nodes of lung cancer patients. For histopathologically positive lymph nodes from a complete resection, the investigators would like to analyse tumor tissue by allelotyping and comparing these results with those observed in the primary lung tumor to establish a cartography of molecular alteration in resected lung cancer. For non histopathologically positive lymph nodes, the investigators would like to research the presence (or not) of micrometastasis by allele-specific PCR (polymerase chain reaction).

Detailed Description

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Genetic: It is a prospective study during two years with three years for follow-up. No control group is recruited.

Conditions

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Lung Cancer

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Patients with resectable non-small cell lung cancer (stage I to IIIA), with a complete resection of the tumor and paired lymph nodes.
* Informed consent is required.

Exclusion Criteria

* Another cancer
* Chemotherapy before surgical treatment
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Strasbourg, France

OTHER

Sponsor Role lead

Responsible Party

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University Hospital, Strasbourg, France

Principal Investigators

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Michèle BEAU-FALLER, MD

Role: PRINCIPAL_INVESTIGATOR

Laboratoire de Biochimie et de Biologie Moléculaire, Hôpital de Hautepierre

Locations

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Service de Chirurgie Thoracique, Hôpital Civil

Strasbourg, , France

Site Status

Service de Pneumologie, Hôpital Lyautey

Strasbourg, , France

Site Status

Laboratoire de Biochimie et de Biologie Moléculaire, Hôpital de Hautepierre

Strasbourg, , France

Site Status

Service d'Anatomie Pathologique, Hôpital de Hautepierre

Strasbourg, , France

Site Status

Service de Pneumologie, Hôpital de Hautepierre

Strasbourg, , France

Site Status

Countries

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France

Other Identifiers

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3207

Identifier Type: -

Identifier Source: org_study_id

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