Fibroscan Study in HCC

NCT ID: NCT01796145

Last Updated: 2025-11-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Clinical Phase

NA

Total Enrollment

207 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-02-27

Study Completion Date

2027-12-31

Brief Summary

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In patients with HCC undergoing therapy 1. We aim to determine the prognostic significance of liver stiffness in patients with HCC 2. We aim to determine the rate and severity of complications of treatment and its association with liver stiffness in patients with HCC

Detailed Description

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Conditions

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Confirmed Diagnosis of Hepatocellular Carcinoma Patients Who Are Scheduled to Undergo Transarterial Chemobolization, Systemic Therapy Surgery Child's A to C Cirrhosis

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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TACE

Group Type EXPERIMENTAL

Fibroscan

Intervention Type OTHER

Systemic Therapy

Group Type EXPERIMENTAL

Fibroscan

Intervention Type OTHER

Surgery

Group Type EXPERIMENTAL

Fibroscan

Intervention Type OTHER

Interventions

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Fibroscan

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Clinical diagnosis of HCC
* Patients who are scheduled to undergo therapy, either TACE systemic therapy or surgery

1. For TACE cohort, patients undergoing first cycle TACE are eligible.
2. For systemic therapy cohort, patients undergoing first-line systemic therapy are eligible.
3. For surgery cohort, patient undergoing surgery are eligible.
* Prior surgery or loco-ablative therapy (e.g. Radiofrequency ablation, microwave, percutaneous ethanol injection) is allowed
* Child's A to Child's C liver function

Exclusion Criteria

* ECOG performance status \> 2
* Poorly controlled ascites
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Chinese University of Hong Kong

OTHER

Sponsor Role lead

Responsible Party

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CCTU

Comprehensive Cancer Trials Unit

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Stephen Lam Chan, FHKCP

Role: PRINCIPAL_INVESTIGATOR

Chinese University of Hong Kong

Locations

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Department of Clinical Oncology, Prince of Wales Hospital

Hong Kong, , Hong Kong

Site Status

Countries

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Hong Kong

Other Identifiers

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HCC033

Identifier Type: -

Identifier Source: org_study_id

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