A Study of Pancreatic Cancer in Xenografts From Liver Metastases

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

31 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-01-31

Study Completion Date

2022-11-30

Brief Summary

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This is a feasibility study to perform image-guided liver biopsies in 25 patients who have pancreatic cancer with liver metastasis (cancer in the pancreas that has spread to the liver). This will contribute with samples for the bio-bank (bank of tumors) and develop xenografts (human tumors growing in mice) for further analysis of genes.

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Detailed Description

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This study might bring a better understanding of the metastatic pancreatic cancer and evaluate the differences between the metastatic and the primary pancreatic cancer (the type that does not have metastasis).

Conditions

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Pancreatic Cancer Liver Metastases Tumor Tissue Biopsy Blood Samples

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Pancreatic cancer with liver metastases

Tumor tissue biopsy, blood samples

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Minimum age of 18 years old
* Pancreatic cancer with liver metastasis
* No contraindication to image-guided biopsy of liver metastasis, including uncontrolled bleeding diathesis, uncontrolled malignant pain, inability to lie supine etc) and no significant hepatic dysfunction.
* Provide written informed consent
* ECOG 0,1 or 2

Exclusion Criteria

* Inability to lie supine for more than 30 minutes
* ECOG 3 or more
* Serious medical risk factors involving any of the major organ systems or including uncontrolled bleeding diathesis, uncontrolled malignant pain, inability to lie supine etc) and no significant hepatic dysfunction.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No