Influence of Bag Volume Variation on the Reproducibility of Inert Gas Rebreathing

NCT ID: NCT01762917

Last Updated: 2013-01-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

45 participants

Study Classification

OBSERVATIONAL

Study Start Date

2007-09-30

Study Completion Date

2010-12-31

Brief Summary

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Non-invasive inert gas rebreathing (IGR) based on the Fick Principle showed promising results in the determination of pulmonary blood flow (PBF). The volume of the rebreathing bag (Vbag) is proposed by the system, however, elderly patients or those suffering from high grade pulmonary diseases might be unable to entirely rebreathe this volume and therefore fail to completely mix the test gases. The aim of our study is to evaluate the effect of adapting Vbag on the reproducibility of IGR measurements in patients with obstruction (group A), restriction (group B) and pulmonary healthy controls (group C).

Detailed Description

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Conditions

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Chronic Obstructive Pulmonary Disease Bronchial Asthma Restrictive Pulmonary Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Obstruction

Patients suffering from pulmonary obstruction

No interventions assigned to this group

Restriction

Patients suffering from pulmonary restriction

No interventions assigned to this group

Controls

Pulmonary healthy controls

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* ability to perform rebreathing maneuver
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Universitätsmedizin Mannheim

OTHER

Sponsor Role lead

Responsible Party

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Joachim Saur

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University Hospital Mannheim

Mannheim, , Germany

Site Status

Countries

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Germany

Other Identifiers

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IGR_Vbag_MA

Identifier Type: -

Identifier Source: org_study_id

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