Economic Impact of Switching From Metoprolol to Nebivolol for Hypertension Treatment

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

3000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-10-31

Study Completion Date

2013-07-31

Brief Summary

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This is a retrospective data analysis of patients with high blood pressure (hypertension) who took metoprolol for a minimum of 6 months who then switched to taking nebivolol for a minimum of 6 month to treat hypertension. These patients will be identified from a large medical claims database. This study tests the hypothesis (alternative, higher or lower) that average patient monthly health care administrative cost changes after switching from metoprolol to nebivolol.

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Detailed Description

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Conditions

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Hypertension

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Metoprolol to Nebivolol

Patients with high blood pressure (hypertension) who were continuously treated with metoprolol for a minimum of 6 months prior to switching to nebivolol. Patients were then continuously treated with nebivolol for a minimum of 6 months.

Metoprolol

Intervention Type DRUG

Metoprolol, oral administration

Nebivolol

Intervention Type DRUG

Nebivolol, oral administration

Interventions

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Metoprolol

Metoprolol, oral administration

Intervention Type DRUG

Nebivolol

Nebivolol, oral administration

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Be at least 18 years old at initiation of metoprolol (or first date on metoprolol treatment between 2007 and 2011)
* Had one or more inpatient or outpatient claims with a primary or non-primary diagnosis of hypertension (ICD-9-CM 401.xx-405.xx)
* Received nebivolol treatment continuously (defined as supply gap \<30 days) for at least 6 months after initiation
* Received metoprolol treatment continuously for at least 6 months prior to switching to (initiation of) nebivolol (defined as metoprolol was discontinued whereas a prescription for nebivolol was filled)
* Had at least 12 months of continuous enrollment (as verified using enrollment file): 6 month prior to nebivolol initiation and 6 months following nebivolol initiation.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No