Minimally Invasive Three-dimensional Knee Kinematic Assessment and Surgical Guidance Using Ultrasonic Rigid Registration

NCT ID: NCT01674816

Last Updated: 2024-02-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-12-01

Study Completion Date

2026-12-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Problem:

Currently, no system allows precise kinematic assessment of the knee and accurate guiding of orthopedic surgical actions in a minimally invasive fashion. However, such a system would prove useful in the clinical setting to improve the quality of surgical interventions at the knee.

Hypothesis:

A novel knee kinematic assessment and surgical guidance tool using 3D personalized imaging and minimally invasive bony fixation allows precise kinematic assessment and surgical guidance in the routine clinical setting.

Objectives :

* Demonstrating the capacity of the system to precisely measure 3D knee kinematics
* Quantifying the reproducibility of the kinematic measurements
* Measuring the impact of knee surgical procedures on knee kinematics
* Assessing the correlations between measured articular kinematics and clinical results after knee surgery
* Integrating the novel measuring system to the surgical flow of three knee surgical procedures
* Quantifying the precision and reproducibility of the surgical actions guided by the system
* Comparing the clinical results of surgeries guided by the system to those performed with the traditional technique

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

A novel knee kinematic assessment and surgical guidance tool using 3D personalized imaging and minimally invasive bony fixation allows precise kinematic assessment and surgical guidance in the routine clinical setting.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Knee Osteoarthritis Knee Instability 3D Knee Kinematics Precision of Surgical Actions Clinical Outcomes

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Repeated Measurements of Knee Alignment and Kinematics

Patients in the Repeated Measurements Arm will have the kinematic measurement protocol repeated twice before and twice after the surgical procedure; the procedure itself will be performed with the traditional technique, i.e without guidance by the system.

Group Type ACTIVE_COMPARATOR

Repeated Measurements of Knee Alignment and Kinematics

Intervention Type DEVICE

Repeated Measurements of Knee Alignment and Kinematics using tools developed by Eiffel Medtech Inc.

Computer Guidance of Surgical Actions

Patients in the Computer Guidance of Surgical Actions Arm will have the kinematic measurement protocol performed only once before and once after the surgical procedure; the procedure itself will be performed with guidance by the system.

Group Type ACTIVE_COMPARATOR

Computer Guidance of Surgical Actions

Intervention Type DEVICE

Computer Guidance of Surgical Actions using tools developed by Eiffel Medtech Inc.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Repeated Measurements of Knee Alignment and Kinematics

Repeated Measurements of Knee Alignment and Kinematics using tools developed by Eiffel Medtech Inc.

Intervention Type DEVICE

Computer Guidance of Surgical Actions

Computer Guidance of Surgical Actions using tools developed by Eiffel Medtech Inc.

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients awaiting a knee surgery (total knee arthroplasty (TKA), high tibial osteotomy (HTO), anterior cruciate ligament reconstruction(ACLR))

Exclusion Criteria

* Active infection
* Atypical morphology and/or alignment of the lower limbs
* Knee instability (other than secondary to ACL deficiency in patients awaiting ACLR)
* Knee flexion contracture of 10 degrees or more
* Knee flexion of less than 120 degrees
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Eiffel Medtech

INDUSTRY

Sponsor Role collaborator

Centre hospitalier de l'Université de Montréal (CHUM)

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Frédéric Lavoie, MD, MSc, FRCSC

Role: PRINCIPAL_INVESTIGATOR

CHUM

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Centre Hospitalier de l'Université de Montréal (CHUM)

Montreal, Quebec, Canada

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Canada

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Frédéric Lavoie, MD MSc FRCSC

Role: CONTACT

1-514-890-8000 ext. 25900

Fidaa Al-Shakfa, MSc

Role: CONTACT

1-514-890-8000 ext. 26103

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

CE12.006

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Non-Invasive Distractor During Knee Arthroscopy
NCT06458816 NOT_YET_RECRUITING NA