Social Network Interventions in Rural Honduras

NCT ID: NCT01672580

Last Updated: 2015-03-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

5773 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-08-31

Study Completion Date

2014-10-31

Brief Summary

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This project will examine the spread of health interventions with a randomized control trial design by introducing public health interventions in 32 villages in the Honduran Department of Lempira. Based on identified public health needs in the region, namely improved drinking water and diet, this study will provide training on the use of chlorine (sodium hypochlorite) for water purification and multivitamins for nutritional supplementation. In some villages, individuals selected for their social connectedness will be trained and given coupons that can be redeemed for either chlorine bleach or multivitamins, and these persons will be asked to spread this information and distribute coupons to four people of their choosing. In other villages, individuals selected at random will receive the same training, materials, and instructions. A second wave of coupon distribution will provide coupons to those who received a coupon from the original "seed" groups so that they may disperse these coupons further out in the social networks. Over the following months, study investigators will look at how knowledge of these health practices, and uptake or and adherence to the practices, spreads throughout the villages.

More specifically, the investigators will examine the speed and extent of spreading of these new health practices after introducing them to three different initial "seed" groups: (1) people chosen on the basis of being named as a friend by many people in their village, (2) people chosen based on being named as a friend by a randomly chosen individual, and (3) a group of randomly chosen individuals. It is hypothesized that spread will occur faster and/or to a greater extent when the intervention is started in groups 1 and 2 versus group 3 (control group).

Detailed Description

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Conditions

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Malnutrition Dysentery Social Transmission of Health Behaviors

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

FACTORIAL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Participants

Study Groups

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Random-Cloro

exposure to water chlorination

Group Type ACTIVE_COMPARATOR

exposure to water chlorination

Intervention Type BEHAVIORAL

"Seed" individuals in village are given Clorox bleach for water purification, with training on use and general information on water hygiene, along with coupons to distribute to others in village

Random-Vitamin

exposure to vitamin use

Group Type ACTIVE_COMPARATOR

exposure to vitamin use

Intervention Type BEHAVIORAL

"Seed" individuals in village are given daily adult multivitamin, with training on use and general nutrition information, along with coupons to distribute to others in village

Indegree-Cloro

high in-degree, exposure to water chlorination

Group Type EXPERIMENTAL

exposure to water chlorination

Intervention Type BEHAVIORAL

"Seed" individuals in village are given Clorox bleach for water purification, with training on use and general information on water hygiene, along with coupons to distribute to others in village

high in-degree

Intervention Type BEHAVIORAL

"Seed" individuals for starting intervention are chosen on the basis of high (social network) in-degree

Indegree-Vitamin

high in-degree, exposure to vitamin use

Group Type EXPERIMENTAL

exposure to vitamin use

Intervention Type BEHAVIORAL

"Seed" individuals in village are given daily adult multivitamin, with training on use and general nutrition information, along with coupons to distribute to others in village

high in-degree

Intervention Type BEHAVIORAL

"Seed" individuals for starting intervention are chosen on the basis of high (social network) in-degree

Nominated-Cloro

nominated by random, exposure to water chlorination

Group Type EXPERIMENTAL

exposure to water chlorination

Intervention Type BEHAVIORAL

"Seed" individuals in village are given Clorox bleach for water purification, with training on use and general information on water hygiene, along with coupons to distribute to others in village

nominated by random

Intervention Type BEHAVIORAL

"Seed" individuals for starting intervention are chosen on the basis of being named as a friend/alter of a randomly selected individual

Nominated-Vitamin

nominated by random, exposure to vitamin use

Group Type EXPERIMENTAL

exposure to vitamin use

Intervention Type BEHAVIORAL

"Seed" individuals in village are given daily adult multivitamin, with training on use and general nutrition information, along with coupons to distribute to others in village

nominated by random

Intervention Type BEHAVIORAL

"Seed" individuals for starting intervention are chosen on the basis of being named as a friend/alter of a randomly selected individual

Interventions

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exposure to vitamin use

"Seed" individuals in village are given daily adult multivitamin, with training on use and general nutrition information, along with coupons to distribute to others in village

Intervention Type BEHAVIORAL

exposure to water chlorination

"Seed" individuals in village are given Clorox bleach for water purification, with training on use and general information on water hygiene, along with coupons to distribute to others in village

Intervention Type BEHAVIORAL

high in-degree

"Seed" individuals for starting intervention are chosen on the basis of high (social network) in-degree

Intervention Type BEHAVIORAL

nominated by random

"Seed" individuals for starting intervention are chosen on the basis of being named as a friend/alter of a randomly selected individual

Intervention Type BEHAVIORAL

Other Intervention Names

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Medox Forte Clorox

Eligibility Criteria

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Inclusion Criteria

* Residents of Targeted Communities, ages 15 and up

Exclusion Criteria

* Children younger than age 15
Minimum Eligible Age

15 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Yale University

OTHER

Sponsor Role collaborator

Harvard University

OTHER

Sponsor Role lead

Responsible Party

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Thomas Keegan, Ph.D.

Project Director

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Nicholas A Christakis, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Yale University

Thomas Keegan, PhD

Role: STUDY_DIRECTOR

Yale University

Locations

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Yale University

New Haven, Connecticut, United States

Site Status

Countries

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United States

References

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Kim DA, Hwong AR, Stafford D, Hughes DA, O'Malley AJ, Fowler JH, Christakis NA. Social network targeting to maximise population behaviour change: a cluster randomised controlled trial. Lancet. 2015 Jul 11;386(9989):145-53. doi: 10.1016/S0140-6736(15)60095-2. Epub 2015 May 4.

Reference Type DERIVED
PMID: 25952354 (View on PubMed)

Other Identifiers

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Lempira_Phase2

Identifier Type: -

Identifier Source: org_study_id

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