Technical Accuracy and Userfriendliness of Two Point-of-care C Reactive Protein Devices in Comparison With Laboratory CRP Testing.

NCT ID: NCT01667172

Last Updated: 2012-08-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

300 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-04-30

Study Completion Date

2012-06-30

Brief Summary

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Study to test technical accuracy and userfriendliness of two Point-of-care C Reactive Protein devices (POC CRP devices) in comparison with laboratory CRP testing on children and adults.

Research questions:

1. Are the POC CRP devices technically accurate? Do the measured values agree with CRP values measured at the clinical laboratory?
2. Are the 2 POC CRP devices equivalent ? 2.1. Are the 2 POC CRP devices equally reliable? 2.1.1. Comparison of 2 measurements in the same patient on 1 device (inter-observer-variability) 2.1.2. Comparison of 2 measurements in the same patient on 2 identical devices (inter-device-variability) 2.2. Are the 2 Point-of-Care CRP devices equally userfriendly in a general practice surgery? (userfriendliness

Detailed Description

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Conditions

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Healthy and Acutely Ill Children & Adults

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

DOUBLE

Participants Caregivers

Study Groups

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point-of-care test for CRP

Group Type OTHER

Point-of-Care C Reactive Protein measurement on capillary blood

Intervention Type DEVICE

capillary blood fingerstick method to determine C Reactive Protein level in the blood

Interventions

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Point-of-Care C Reactive Protein measurement on capillary blood

capillary blood fingerstick method to determine C Reactive Protein level in the blood

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* children: aged 1 month to 14 years
* adults: aged 18-65 years

Exclusion Criteria

* children and adults not understanding Dutch language
Minimum Eligible Age

1 Month

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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KU Leuven

OTHER

Sponsor Role lead

Responsible Party

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Jan Verbakel

Research Assistant

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Huisartspraktijken

Leuven, Vlaams-Brabant, Belgium

Site Status

Medisch Centrum voor Huisartsen

Leuven, Vlaams-Brabant, Belgium

Site Status

UZ Leuven

Leuven, Vlaams-Brabant, Belgium

Site Status

Countries

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Belgium

References

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Van den Bruel A, Thompson MJ, Haj-Hassan T, Stevens R, Moll H, Lakhanpaul M, Mant D. Diagnostic value of laboratory tests in identifying serious infections in febrile children: systematic review. BMJ. 2011 Jun 8;342:d3082. doi: 10.1136/bmj.d3082.

Reference Type BACKGROUND
PMID: 21653621 (View on PubMed)

Van den Bruel A, Haj-Hassan T, Thompson M, Buntinx F, Mant D; European Research Network on Recognising Serious Infection investigators. Diagnostic value of clinical features at presentation to identify serious infection in children in developed countries: a systematic review. Lancet. 2010 Mar 6;375(9717):834-45. doi: 10.1016/S0140-6736(09)62000-6. Epub 2010 Feb 2.

Reference Type BACKGROUND
PMID: 20132979 (View on PubMed)

Other Identifiers

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S54271

Identifier Type: -

Identifier Source: org_study_id