Oxidative Stress in Obstructive Sleep Apnea: Correlation of Biomarkers and Nasal CPAP Compliance

NCT ID: NCT01661699

Last Updated: 2014-08-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

24 participants

Study Classification

OBSERVATIONAL

Study Start Date

2011-08-31

Study Completion Date

2014-07-31

Brief Summary

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The purpose of this study is to check blood and urine levels to further define markers/tests in the blood and urine that would be useful in following patients with obstructive sleep apnea and then to see if by wearing CPAP every night, these markers can be reduced. This research is being done because currently there are no effective blood or urine markers to determine how well CPAP is working.

Detailed Description

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The goal of this study is to further define biomarkers that would be useful in following patients with obstructive sleep apnea and examining their response to compliance to therapy with CPAP. To date no correlation between biomarkers of oxidative stress and compliance to CPAP has been measured. CPAP is the most effective treatment for obstructive sleep apnea and has been show to reduce blood pressure and decrease oxidative stress.

Conditions

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Sleep Apnea, Obstructive

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Sleep apnea

Those suspected of sleep apnea and scheduled for polysomnography and treated with CPAP therapy.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Men and Women over 18 years suspected of having sleep apnea

Exclusion Criteria

* Those under 18 years or not suspected of having sleep apnea
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Georgetown University

OTHER

Sponsor Role lead

Responsible Party

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Christina Reichner, M.D.

M.D., Associate Professor Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Cristina Reichner, MD

Role: PRINCIPAL_INVESTIGATOR

Georgetown University

Locations

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Georgetown University Hospital

Washington D.C., District of Columbia, United States

Site Status

Countries

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United States

Other Identifiers

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2011-416

Identifier Type: -

Identifier Source: org_study_id

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