Clinical Characteristics and Molecular Mechanism of Patients With Obstructive Sleep Apnea

NCT ID: NCT07277608

Last Updated: 2025-12-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-08-07

Study Completion Date

2033-08-07

Brief Summary

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To clarify the clinical features of patients with obstructive sleep apnea; To construct a multi-omics database of patients with obstructive sleep apnea, and compare the effects of different degrees of sleep apnea on prognosis, immunity, and metabolism. The medium and long-term prognosis, complications, comorbidities, risk factors, and immune and metabolic dynamics of patients with sleep apnea after treatment were studied. To elucidate the biomarkers and therapeutic targets associated with obstructive sleep apnea.

Detailed Description

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Conditions

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Obstructive Sleep Apnea

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Severe OSA

No interventions assigned to this group

Non-severe OSA

No interventions assigned to this group

Healthy controls

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients with suspected obstructive sleep apnea (OSA) admitted to the sleep center of the respiratory Department of Beijing Chaoyang Hospital, Capital Medical University.
* Volunteer to participate in the study and sign an informed consent, and can complete at least 1 year of follow-up.

Exclusion Criteria

* Patients with obstructive sleep apnea who have been treated with impermanent positive pressure ventilation;
* Pregnant or lactating women;
* Patients with severe respiratory failure requiring mechanical ventilation;
* Patients with severe heart, lung, liver, kidney, and central nervous system damage;
* Refuse to participate in follow-up visits and/or take biological samples.
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Capital Medical University

OTHER

Sponsor Role lead

Responsible Party

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Zhaohui Tong

professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Beijing Chaoyang hospital affiliated to Capital Medical University

Beijing, Beijing Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Zhiling Zhao

Role: CONTACT

+86 186 1280 8859

Facility Contacts

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Zhiling Zhao

Role: primary

+86 186 1280 8859

Other Identifiers

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2023-ke-450

Identifier Type: -

Identifier Source: org_study_id

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