28mm Ceramic-on-Ceramic Total Hip Replacement Study

NCT ID: NCT01657435

Last Updated: 2019-11-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

185 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-05-01

Study Completion Date

2019-09-24

Brief Summary

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This study is intended to gather medium (0-5 years) and long-term (6-10 years) information regarding the performance and safety of the commercially available Ceramax™ Ceramic on Ceramic Total Hip System. This is a two-phased study consisting of a clinical follow-up phase and a clinical outcomes phase.

In Phase One (0-5 years), diagnostic, demographic and operative information will be gathered for each subject enrolled in this study. In addition, Harris Hip Evaluations, subjective evaluations and radiographs will be completed annually.

In Phase Two (6 - 10 years), a subjective outcomes questionnaire and a SF-12 Health Survey will be mailed to subjects annually.

Detailed Description

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This is a prospective, non-randomized study of the 28mm Ceramic on Ceramic (COC) device. This study will follow each subject through 10 years postoperatively and will consist of:

1. a clinical follow-up phase and
2. a clinical outcomes phase.

Radiographic and clinical follow-up exams will take place at six-weeks, six-months and then annually through year 5 for each subject. For years 6 - 10, a communication will be sent to each subject in order to collect survivorship and general health information. This communication will ask whether the COC device is still in vivo and, if not, when the revision surgery took place, why, and which components were removed, if applicable. In addition, subjects will be asked to complete a SF-12 Health Survey at each 6 to 10-year follow-up interval. A self-addressed, stamped envelope will be provided to facilitate information return and privacy.

Conditions

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Non-inflammatory Degenerative Joint Disease Osteoarthritis Avascular Necrosis Post-traumatic Arthritis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Ceramax COC 28mm Acetabular Cup

The 28 mm ceramic acetabular bearing insert component is manufactured from high purity, dense alumina matrix composite ceramic. The inserts secure to DePuy's Pinnacle acetabular shells by means of an interlocking mechanical taper. The Pinnacle acetabular shell is a hemispherical type acetabulum replacement prosthesis, is available in a range of outer diameter (OD) sizes, and is used with a 28mm femoral head. Pinnacle 100 shells will be used in this study. The BIOLOX® delta ceramic femoral head components are manufactured from the same ceramic material as the acetabular bearing insert components. The femoral head is secured to the femoral stem component with an interlocking taper.

Ceramax Acetabular System

Intervention Type DEVICE

28mm Ceramic-on-ceramic Acetabular Cup System

Interventions

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Ceramax Acetabular System

28mm Ceramic-on-ceramic Acetabular Cup System

Intervention Type DEVICE

Other Intervention Names

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Ceramic-on-ceramic 28 mm Acetabular Cup

Eligibility Criteria

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Inclusion Criteria

* Subjects who were previously enrolled in the COC28 IDE study, or
* Newly recruited individuals who are qualified based on the approved labeling of the device, and;
* Individuals who are willing and able to provide informed patient consent for participation in the study;
* Individuals who are willing and able to return for follow-up as specified by the study protocol; and
* Individuals who are willing and able to complete the Hip Outcomes questionnaire and SF-12 Health Survey as specified by the study protocol

Exclusion Criteria

* In the opinion of the Investigator, the individual does not qualify based upon approved labeling requirements.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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DePuy Orthopaedics

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Tammy L ODell, BS CCRC CCRA

Role: STUDY_DIRECTOR

DePuy Orthopaedics

Locations

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Joint Surgeons of Sacremento

Sacramento, California, United States

Site Status

Colorado Joint Replacement

Denver, Colorado, United States

Site Status

Fort Collins, Colorado, United States

Site Status

Florida University

Gainesville, Florida, United States

Site Status

FOI Florida Orthopaedic Institute

Tampa, Florida, United States

Site Status

New England Baptist Hospital

Boston, Massachusetts, United States

Site Status

Tufts - New England Medical Center

Boston, Massachusetts, United States

Site Status

Duke University

Durham, North Carolina, United States

Site Status

OrthoCarolina

Winston-Salem, North Carolina, United States

Site Status

Cardinal Orthopaedic Institute

Columbus, Ohio, United States

Site Status

UPenn

Philadelphia, Pennsylvania, United States

Site Status

Anderson Orthopaedic Research Institute

Alexandria, Virginia, United States

Site Status

McGill University - Jewish General Hospital

Montreal, Quebec, Canada

Site Status

Countries

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United States Canada

Other Identifiers

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09001

Identifier Type: -

Identifier Source: org_study_id

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