Randomized Clinical Trial of Ceramic Bearing Primary Total Hip Arthroplasty

NCT ID: NCT01522014

Last Updated: 2021-07-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

92 participants

Study Classification

INTERVENTIONAL

Study Start Date

1997-11-30

Study Completion Date

2009-06-30

Brief Summary

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Primary total hip arthroplasty (THA) has been a very successful surgical intervention in the geriatric population. Numerous studies have reported good mid and long term results of THA in patients over the age of 60 years. With the reported high success rate of this surgical intervention, the THA surgery is being performed in younger patients who have significant joint disease.

A clinical trial, using a randomized blinded design, was undertaken to compare the functional outcome of 1) alumina heads/alumina liners, and 2) alumina head/Crossfire polyethylene liners in patients 60 years of age or younger with non-inflammatory arthritis of the hip.

Subjects were assessed preoperatively and at one and five years postoperatively. Ten-year follow-up is currently underway.

The primary outcome measure is the WOMAC Osteoarthritis Index. Secondary measures were the RAND-12, as well as measurement of complication and revision rates. The patient's demand on the implant as calculated by the patient's age, weight, health status and activity level was also measured.

Detailed Description

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Conditions

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Total Hip Replacement

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

Study Groups

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Ceramic on Ceramic

Subjects received a ceramic on ceramic bearing total hip replacement.

Group Type ACTIVE_COMPARATOR

Secure-Fit™ arc-deposited Hydroxylapatite (HA) shell - surface ceramic and an Alumina Bearing Couple (ABC) ceramic insert and Ceramic C-taper head

Intervention Type DEVICE

Ceramic-on-Highly Crosslinked Polyethylene

Group Type ACTIVE_COMPARATOR

Secure-Fit™ arc-deposited hydroxylapatite shell, a Crossfire® insert and a Ceramic C-taper head

Intervention Type DEVICE

Interventions

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Secure-Fit™ arc-deposited Hydroxylapatite (HA) shell - surface ceramic and an Alumina Bearing Couple (ABC) ceramic insert and Ceramic C-taper head

Intervention Type DEVICE

Secure-Fit™ arc-deposited hydroxylapatite shell, a Crossfire® insert and a Ceramic C-taper head

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Males or females scheduled for primary THA to treat non-inflammatory arthritis
* Less than 61 years old at time of surgery
* Able to speak and read the English language or have an available translator
* Dorr Index A or B bone quality on preoperative radiographs
* Willing and able to return for follow-up visits

Exclusion Criteria

* Have femoral or acetabular bone deficiency requiring augmentation
* Ongoing corticosteroid use
* Dorr Index C bone quality on the preoperative radiograph
* Required a prosthesis neck length of greater than five millimeters
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Stryker Canada LP

INDUSTRY

Sponsor Role collaborator

University of Alberta

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Lauren Beaupre, PT, PhD

Role: STUDY_DIRECTOR

University of Alberta

D William C Johnston, MD, FRCS (C)

Role: PRINCIPAL_INVESTIGATOR

Alberta Health services

Locations

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University of Alberta Hospital

Edmonton, Alberta, Canada

Site Status

Royal Alexandra Hospital

Edmonton, Alberta, Canada

Site Status

Countries

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Canada

Other Identifiers

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Pro00000886

Identifier Type: -

Identifier Source: org_study_id

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