Plasma Concentrations of Bupivacaine After Peri-articular Injection in Total Knee Arthroplasty
NCT ID: NCT01636869
Last Updated: 2014-07-28
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE4
43 participants
INTERVENTIONAL
2012-07-31
2014-07-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
BASIC_SCIENCE
NONE
Study Groups
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bupicavaine
Bupivacaine
20 ml of 0.5% bupivacaine for single-shot femoral nerve block will be done at the beginning then another 20 ml of 0.5% bupivacaine for periarticular block will be performed at the end of operation.
Blood sample will be drawn at 60 min after femoral nerve block and before periarticular block, 15, 30, 45, 60 min after periarticular block.
Interventions
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Bupivacaine
20 ml of 0.5% bupivacaine for single-shot femoral nerve block will be done at the beginning then another 20 ml of 0.5% bupivacaine for periarticular block will be performed at the end of operation.
Blood sample will be drawn at 60 min after femoral nerve block and before periarticular block, 15, 30, 45, 60 min after periarticular block.
Eligibility Criteria
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Inclusion Criteria
* ASA I-II
* patient undergo total knee arthroplasty under spinal block and single shot femoral nerve block and periarticular block
Exclusion Criteria
* allergic to bupivacaine
* body weight less than 50 kg
* liver disease
* heart disease
* coagulopathy
* Hct\<35%
* infection at both groin
30 Years
70 Years
ALL
No
Sponsors
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Mahidol University
OTHER
Responsible Party
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Saowaphak Lapmahapaisan
instructor
Locations
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Faculty of Medicine, Siriraj Hospital, Mahidol University
Bangkok, Bangkok, Thailand
Countries
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Other Identifiers
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010/2555
Identifier Type: -
Identifier Source: org_study_id
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