Infrapatellar Nerve Block for Post-operative Knee Arthroscopy Pain Control

NCT ID: NCT01279447

Last Updated: 2014-05-12

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

View full results

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

68 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-01-31

Study Completion Date

2013-08-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to determine whether infrapatellar branch of the saphenous nerve blocks are effective in decreasing analgesic use, promoting earlier mobility, and improving long term outcome scores after knee arthroscopy.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The purpose of this study is to determine whether infrapatellar branch of the saphenous nerve blocks are effective in decreasing analgesic use, promoting earlier mobility, and improving long term outcome scores after knee arthroscopy. Randomized, double-blinded, placebo controlled, study.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Internal Derangement of Knee

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Placebo

A sham infrapatellar block performed under US guidance with normal saline

Group Type SHAM_COMPARATOR

Normal Saline

Intervention Type DRUG

10cc, single dose, US guided injection

Infrapatellar nerve block

An infrapatellar nerve block performed under US guidance with 0.25% bupivacaine

Group Type EXPERIMENTAL

0.25% Bupivacaine

Intervention Type DRUG

10cc, single dose, US guided injection

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

0.25% Bupivacaine

10cc, single dose, US guided injection

Intervention Type DRUG

Normal Saline

10cc, single dose, US guided injection

Intervention Type DRUG

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Nerve block Placebo

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* planned knee arthroscopy with soft tissue intervention
* age 18+
* English speaking

Exclusion Criteria

* contraindications to nerve block: eg neuropathy, type 1 diabetes, coagulopathy
* knee arthroscopy with planned bony intervention
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Northwestern University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Larry Hsu

Resident

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Gordon Nuber, MD

Role: PRINCIPAL_INVESTIGATOR

Northwestern University

Antoun Nader, MD

Role: STUDY_DIRECTOR

Northwestern University

Lawrence Hsu, MD

Role: STUDY_DIRECTOR

Northwestern University

Mark Kendall, MD

Role: STUDY_DIRECTOR

Northwestern University

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Olson Surgical Pavilion

Chicago, Illinois, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

References

Explore related publications, articles, or registry entries linked to this study.

Akkaya T, Ersan O, Ozkan D, Sahiner Y, Akin M, Gumus H, Ates Y. Saphenous nerve block is an effective regional technique for post-menisectomy pain. Knee Surg Sports Traumatol Arthrosc. 2008 Sep;16(9):855-8. doi: 10.1007/s00167-008-0572-4. Epub 2008 Jun 24.

Reference Type BACKGROUND
PMID: 18574578 (View on PubMed)

Lundblad M, Kapral S, Marhofer P, Lonnqvist PA. Ultrasound-guided infrapatellar nerve block in human volunteers: description of a novel technique. Br J Anaesth. 2006 Nov;97(5):710-4. doi: 10.1093/bja/ael241. Epub 2006 Sep 26.

Reference Type BACKGROUND
PMID: 17005509 (View on PubMed)

Arthornthurasook A, Gaew-Im K. Study of the infrapatellar nerve. Am J Sports Med. 1988 Jan-Feb;16(1):57-9. doi: 10.1177/036354658801600110.

Reference Type BACKGROUND
PMID: 3344881 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

STU00026632

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Motor-Sparing Femoral Nerve Block Dose
NCT02909257 TERMINATED PHASE4
Knee Arthroscopy for Pain Control
NCT06701175 WITHDRAWN NA