Stress Echocardiography Versus Coronary Angiography for Left Main Stenosis Detection

NCT ID: NCT01620320

Last Updated: 2013-06-26

Basic Information

• Recruitment Status: WITHDRAWN
• Study Classification: OBSERVATIONAL
• Study Start Date: 2010-07-31
• Study Completion Date: 2013-07-31

Brief Summary

Left main stenosis use to be treated by bypass but with the improvement of angioplasty techniques, an increasing number of patients are submit to left main coronary angioplasty. Consequences of left main intra stent stenosis can be disastrous yet, for the moment, no precise recommendation concerning the follow up of these patients exist. The investigators ought to determine if stress echocardiography can predict left main intra stent stenosis as well (non inferiorly)as control angiography that use to be done.

Detailed Description

All patients of the study will pass coronary angiogram and stress echocardiography (treadmill of dobutamine).

Conditions

Left Main Coronary Artery Disease; Stenosis

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Stress echography

Nine to twelve months after their left main angioplasty, patients will go through a stress echo and then the usual control angiography (done routinely in most patient in our center). Patients will act as their own control.

Stress echocardiography

Intervention Type: OTHER

Patients able to exercise will have a treadmill test + echography; the others will have a dobutamine echography.

Interventions

Stress echocardiography

Patients able to exercise will have a treadmill test + echography; the others will have a dobutamine echography.

Intervention Type: OTHER

Other Intervention Names

Dobutamine echocardiography; Treadmill echocardiography

Eligibility Criteria

Inclusion Criteria

• patients over 18 years old able to give consent and having had left main angioplasty.

Exclusion Criteria

• Bypass on the left anterior descending coronary artery or left circumflex (" protected left main ")
• Treating physician judge that angiography need to be done straightaway
• Follow up elsewhere than the CHUS
• Patient refusal
• Pregnant women
• Stress echo contraindication(Severe high blood pressure or malignant arrhythmia)or condition that limits interpretation (Left bundle branch block or pacemaker rhythm)

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Université de Sherbrooke

OTHER

Sponsor Role: lead

Responsible Party

Paul Farand

Doctor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Paul Farand, Cardiologue

Role: PRINCIPAL_INVESTIGATOR

Centre de recherche du Centre hospitalier universitaire de Sherbrooke

Locations

Centre Hospitalier Universitaire de Sherbrooke, departement de cardiologie

Sherbrooke, Quebec, Canada

Countries

Canada

Other Identifiers

projet #10-011

Identifier Type: -

Identifier Source: org_study_id